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温控激光焊接系统及其在皮肤切口缝合中的临床应用。

Temperature-controlled laser-soldering system and its clinical application for bonding skin incisions.

作者信息

Simhon David, Gabay Ilan, Shpolyansky Gregory, Vasilyev Tamar, Nur Israel, Meidler Roberto, Hatoum Ossama Abu, Katzir Abraham, Hashmonai Moshe, Kopelman Doron

机构信息

Tel Aviv University, School of Physics and Astronomy, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv 69978, Israel.

Israel Institute of Technology, Faculty of Medicine, Technion, Haifa 32000, Israel.

出版信息

J Biomed Opt. 2015;20(12):128002. doi: 10.1117/1.JBO.20.12.128002.

Abstract

Laser tissue soldering is a method of repairing incisions. It involves the application of a biological solder to the approximated edges of the incision and heating it with a laser beam. A pilot clinical study was carried out on 10 patients who underwent laparoscopic cholecystectomy. Of the four abdominal incisions in each patient, two were sutured and two were laser soldered. Cicatrization, esthetical appearance, degree of pain, and pruritus in the incisions were examined on postoperative days 1, 7, and 30. The soldered wounds were watertight and healed well, with no discharge from these wounds or infection. The total closure time was equal in both methods, but the net soldering time was much shorter than suturing. There was no difference between the two types of wound closure with respect to the pain and pruritus on a follow-up of one month. Esthetically, the soldered incisions were estimated as good as the sutured ones. The present study confirmed that temperature-controlled laser soldering of human skin incisions is clinically feasible, and the results obtained were at least equivalent to those of standard suturing.

摘要

激光组织焊接是一种修复切口的方法。它包括将生物焊料应用于切口的对合边缘,并用激光束加热。对10例行腹腔镜胆囊切除术的患者进行了一项初步临床研究。在每位患者的四个腹部切口中,两个进行缝合,两个进行激光焊接。在术后第1天、第7天和第30天检查切口的瘢痕形成、美观外观、疼痛程度和瘙痒情况。焊接的伤口不漏水且愈合良好,这些伤口没有渗液或感染。两种方法的总闭合时间相同,但净焊接时间比缝合短得多。在随访一个月时,两种伤口闭合方式在疼痛和瘙痒方面没有差异。从美观角度看,焊接切口与缝合切口效果相当。本研究证实,对人体皮肤切口进行温度控制的激光焊接在临床上是可行的,并且所获得的结果至少与标准缝合相当。

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