Zhao Shi-Chang, Zhang Chang-Qing, Zhang Chun-Lin
Department of Orthopaedics, Shanghai Sixth People's Hospital, Shanghai Jiaotong University, Shanghai 200233, P.R. China.
Department of Orthopaedics, Shanghai Tenth People's Hospital, Tongji University, Shanghai 200072, P.R. China.
Oncol Lett. 2015 Nov;10(5):3279-3285. doi: 10.3892/ol.2015.3627. Epub 2015 Aug 24.
The present report describes a case of a 44-year-old female patient who presented with a palpable mass of the left thigh. A diagnosis of parosteal osteosarcoma (POS) at the femoral diaphysis was made following a diagnostic workup. Previous reports of long bone diaphyseal POS are rare. A long diaphyseal segment of the femur containing the tumor was resected along with a healthy margin of soft tissues, and the damaged bone was reconstructed with a custom-made intercalary endoprosthesis. Subsequent pathological examination of the surgical sample confirmed the diagnosis of POS. No local recurrence or distant metastasis was observed, and the patient had a positive Musculoskeletal Tumor Society score of 28/30 (93.3%) at the 28-month post-surgery follow-up. The present study describes the clinical, radiological, and pathological features of this rare type of osteosarcoma.
本报告描述了一例44岁女性患者,其左大腿出现可触及肿块。经过诊断检查后,确诊为股骨干骨旁骨肉瘤(POS)。此前关于长骨干骺端POS的报道很少。切除了包含肿瘤的股骨长干骺端节段以及健康的软组织边缘,并用定制的节段性内置假体对受损骨骼进行了重建。随后对手术样本的病理检查证实了POS的诊断。未观察到局部复发或远处转移,在术后28个月的随访中,患者的肌肉骨骼肿瘤学会评分为28/30(93.3%),结果呈阳性。本研究描述了这种罕见骨肉瘤类型的临床、放射学和病理学特征。