Benharroch Daniel, Shvarts Shifra, Jotkowitz Alan, Shelef Ilan
1. Head of the Hematopathology Unit, Department of Pathology, Soroka University Medical Center and Faculty of Health Sciences, Ben Gurion University of the Negev;
2. The Moshe Privas Centre for Medical Education, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel;
J Cancer. 2016 Jan 1;7(1):115-20. doi: 10.7150/jca.13555. eCollection 2016.
Reports on a marked reduction of the number of autopsies performed worldwide to less than 5% of hospital deaths remain without a satisfactory explanation. The premature disappearance of the autopsy might represent a medical tragedy of a major order. One of the causes for the decrease in autopsies is poorly documented: we suspect that the attending physician might show some reluctance when requesting a consent for an autopsy from the bereaved family. Moreover, this officer might consider that the post mortem will add little information to that already obtained from the computerized tomography scanner or the magnetic resonance imaging.
In order to confirm our hypothesis, we carried out a review of 300 articles indexed as "radiologic-histologic correlation", 118 of which were selected for a significant correlation. From the abstracts, we retrieved the type of the article, the degree of correlation as assessed by the authors and the form of imaging employed, and we computed them.
RESULTS & CONCLUSIONS: The most striking correlation was observed in the small prospective series. An additional search for the "radiologic-autopsy correlation" supported a marked reduction in the number of post-mortems, especially those related with prospective studies. Based on the present study, we cannot determine precisely the role of the house officer in this tragedy. We may have demonstrated, however, that the modern radiologic methods have not yet reached a high enough performance quality to achieve the status of a candidate substitute for the autopsy.
全球范围内进行尸检的数量显著减少,降至医院死亡人数的5%以下,对此尚无令人满意的解释。尸检过早消失可能是一场重大的医学悲剧。尸检数量减少的原因之一记录不详:我们怀疑主治医生在向死者家属请求尸检同意时可能会有所犹豫。此外,该医生可能认为尸检对已从计算机断层扫描仪或磁共振成像中获得的信息补充甚少。
为了证实我们的假设,我们对300篇索引为“放射学-组织学相关性”的文章进行了综述,其中118篇因显著相关性而被选中。从摘要中,我们检索了文章类型、作者评估的相关程度以及所采用的成像形式,并进行了计算。
在小型前瞻性系列研究中观察到最显著的相关性。对“放射学-尸检相关性”的进一步检索支持了尸检数量的显著减少,尤其是与前瞻性研究相关的尸检。基于本研究,我们无法准确确定住院医生在这场悲剧中的作用。然而,我们可能已经证明,现代放射学方法尚未达到足够高的性能质量,无法成为尸检的替代候选方法。