Mammas Ioannis N, Theodoridou Maria, Koutsaftiki Chryssie, Bertsias George, Sourvinos George, Spandidos Demetrios A
Department of Clinical Virology, School of Medicine, University of Crete, Heraklion, Heraklion, Greece.
First Department of Paediatrics, 'Aghia Sophia' Children's Hospital, University of Athens School of Medicine, Athens, Greece.
J Pediatr Adolesc Gynecol. 2016 Aug;29(4):362-6. doi: 10.1016/j.jpag.2015.12.007. Epub 2015 Dec 24.
In this study we aimed to explore financial and other sociodemographic factors that affect nonvaccination against the human papillomavirus (HPV) in Greece, one of the first European Union countries to introduce the vaccination against HPV into its National Immunization Programme in 2008. DESIGN, SETTING, PARTICIPANTS, INTERVENTIONS, AND MAIN OUTCOME MEASURES: Six hundred thirty-two female adolescents (aged 11-16 years) from Greece completed a pilot cross-sectional questionnaire-based survey (ELEFTHERIA study) from 2008 to 2014.
Overall, only 8.9% (56 of 632) of the female adolescents reported that they had received all 3 doses of the HPV vaccination. The HPV vaccination uptake rates increased gradually from 3.2% (3 of 95) in 2008 to 17.1% (14 of 82) in 2011. However, it abruptly decreased to 2.1% (2 of 95) in 2012 and it reached 9.2% (8 of 87) in 2013 and 11.5% (11 of 96) in 2014. The most common factors for nonvaccination included fear of side effects, which decreased (Spearman ρ = -0.860; P = .024) and financial issues, which increased statistically significantly (Spearman ρ = 0.890; P = .012) during the years 2008 to 2014.
In our study we addressed the novel topic of the association of financial issues with HPV vaccination compliance and highlighted the urgent need to provide and maintain health insurance coverage to children in Greece, a country in financial crisis.
在本研究中，我们旨在探究影响希腊人乳头瘤病毒（HPV）疫苗未接种情况的经济因素及其他社会人口学因素。希腊是2008年最早将HPV疫苗纳入国家免疫规划的欧盟国家之一。设计、地点、参与者、干预措施及主要结局指标：2008年至2014年期间，632名来自希腊的11至16岁女性青少年完成了一项基于问卷调查的试点横断面调查（ELEFTHERIA研究）。
总体而言，只有8.9%（632人中的56人）的女性青少年报告称她们接种了全部3剂HPV疫苗。HPV疫苗接种率从2008年的3.2%（95人中的3人）逐渐上升至2011年的17.1%（82人中的14人）。然而，2012年该接种率骤降至2.1%（95人中的2人），2013年升至9.2%（87人中的8人），2014年升至11.5%（96人中的11人）。未接种疫苗的最常见因素包括对副作用的恐惧，在2008年至2014年期间该因素呈下降趋势（斯皮尔曼相关系数ρ = -0.860；P = 0.024），而经济问题在这几年中则有显著上升（斯皮尔曼相关系数ρ = 0.890；P = 0.012）。
在我们的研究中，我们探讨了经济问题与HPV疫苗接种依从性之间关联这一新颖话题，并强调了在处于金融危机的希腊为儿童提供并维持医疗保险覆盖范围的迫切需求。
