Wang Weiyi
National Engineering Laboratory for Internet Medical Systems and Applications, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe Road, Erqi District, Zhengzhou, Henan, 450052, China.
National Telemedicine Center of China, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Int J Equity Health. 2025 Jan 8;24(1):4. doi: 10.1186/s12939-024-02370-6.
Ensuring vaccine access is a prerequisite for promoting human papilloma virus (HPV) vaccination. Although HPV vaccination efforts in China have primarily focused on young females, little research has examined the difficulties they face in accessing the HPV vaccine and its impact on vaccine uptake and intention. This study analyzed the overall perception of access difficulties to HPV vaccines, as well as three specific vaccine access difficulties, and examined their influencing factors among female university students in China. We also examined the associations between overall and specific vaccine access difficulties and HPV vaccination intention and uptake.
A cross-sectional study was conducted among female university students from eight universities or colleges in Zhejiang Province, China, from December 2020 to January 2021. Logistic regressions were used to identify factors associated with both overall and specific perceptions of vaccine access difficulties. A multivariable logistic regression model and a multiple linear regression model were used to explore factors influencing HPV vaccine uptake and vaccine intention by controlling for potential confounding factors, respectively.
A total of 3176 female university students were included in this study. The proportion of female students perceiving overall difficulty in obtaining HPV vaccine, as well as difficulties in accessing the desired type of HPV vaccine, HPV vaccination centers, and HPV vaccination information, were 60.6%, 57.7%, 60.7%, and 54.0%, respectively. Perceived overall difficulty in obtaining HPV vaccine, as well as difficulties in accessing the desired type of HPV vaccine, HPV vaccination centers, and HPV vaccination information were associated with HPV vaccine uptake and intention.
Chinese female university students generally perceived various difficulties in accessing HPV vaccine. It is crucial to improve access to HPV vaccine, optimize the layout and service quality of HPV vaccination centers, and enhance the dissemination and transparency of HPV vaccine information. More efforts are needed to provide a strong guarantee for HPV vaccination uptake among female university students.
确保疫苗可及性是促进人乳头瘤病毒（HPV）疫苗接种的前提条件。尽管中国的HPV疫苗接种工作主要集中在年轻女性，但很少有研究探讨她们在获取HPV疫苗时所面临的困难及其对疫苗接种率和接种意愿的影响。本研究分析了对HPV疫苗可及性困难的总体认知，以及三种具体的疫苗获取困难，并探讨了中国女大学生中这些困难的影响因素。我们还研究了总体和具体的疫苗获取困难与HPV疫苗接种意愿和接种率之间的关联。
于2020年12月至2021年1月在中国浙江省八所高校的女大学生中开展了一项横断面研究。采用逻辑回归来确定与疫苗获取困难的总体认知和具体认知相关的因素。分别使用多变量逻辑回归模型和多元线性回归模型，通过控制潜在混杂因素来探索影响HPV疫苗接种率和接种意愿的因素。
本研究共纳入3176名女大学生。认为获取HPV疫苗总体困难的女学生比例，以及在获取所需类型的HPV疫苗、HPV疫苗接种中心和HPV疫苗接种信息方面存在困难的比例分别为60.6%、57.7%、60.7%和54.0%。感知到的获取HPV疫苗总体困难，以及获取所需类型的HPV疫苗、HPV疫苗接种中心和HPV疫苗接种信息方面的困难与HPV疫苗接种率和接种意愿相关。
中国女大学生普遍认为在获取HPV疫苗方面存在各种困难。改善HPV疫苗的可及性、优化HPV疫苗接种中心的布局和服务质量，以及加强HPV疫苗信息的传播和透明度至关重要。需要做出更多努力，为女大学生的HPV疫苗接种提供有力保障。
