Department of Cardiology, Heart and Lung Centrum, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA, Leiden, the Netherlands.
Department of Cardiology, AHEPA University Hospital, Thessaloniki, Greece.
Eur J Heart Fail. 2016 May;18(5):469-81. doi: 10.1002/ejhf.466. Epub 2016 Jan 4.
Aortic stenosis (AS) is the most frequent degenerative valvular heart disease in Western countries and its prevalence increases in parallel with the ageing process of the population. Heart failure (HF), defined by the presence of reduced left ventricular ejection fraction, may be present in up to a quarter of patients with severe AS, posing diagnostic and management challenges. The present article reviews the prevalence of HF in severe AS patients, discusses the diagnostic challenges and the advances in multimodality imaging to identify the patients that may benefit from surgical or transcatheter aortic valve replacement, and summarizes the current evidence on management for this group of patients.
主动脉瓣狭窄(AS)是西方国家最常见的退行性心脏瓣膜病,其患病率随着人口老龄化进程而增加。心力衰竭(HF)定义为左心室射血分数降低,在多达四分之一的严重 AS 患者中可能存在,这给诊断和管理带来了挑战。本文回顾了严重 AS 患者 HF 的患病率,讨论了诊断挑战和多模态成像的进展,以确定可能从手术或经导管主动脉瓣置换中获益的患者,并总结了目前关于该患者群体管理的证据。