希腊血友病患者的黄疸、乙肝表面抗原及抗体情况

Jaundice and hepatitis B surface antigen and antibody in Greek haemophiliacs.

作者信息

Yannitsiotis A, Bossinakou I, Louizou C, Mandalaki T

出版信息

Scand J Haematol Suppl. 1977;30:11-5. doi: 10.1111/j.1600-0609.1977.tb01512.x.

DOI:10.1111/j.1600-0609.1977.tb01512.x

Abstract

The incidence of hepatitis B surface antigen (HBsAg) and antibody (HBsAb) in 101 Greek multitransfused haemophiliacs with or without a previous history of jaundice was studied. Using the haemagglutination inhibition assay, HbsAg was detected in 9.9%, HBsAb in 61.3% and HBsAg plus Ab in 11.8% of the cases. The incidence of jaundice was 14.8%. Liver function was tested by means of Normotest, SGOT, SGPT and serum protein electrophoresis. Abnormal values of liver function tests were found in 47% of the patients. The abnormal findings were related to the presence of HBsAg or Ab and to the history of jaundice. There was no significant difference between the various groups of patients.

摘要

对101名有或无黄疸病史的希腊多次输血血友病患者的乙肝表面抗原（HBsAg）和抗体（HBsAb）发生率进行了研究。采用血凝抑制试验，9.9%的病例检测到HbsAg，61.3%检测到HBsAb，11.8%检测到HBsAg加抗体。黄疸发生率为14.8%。通过正常试验、谷草转氨酶、谷丙转氨酶和血清蛋白电泳检测肝功能。47%的患者肝功能检查值异常。异常结果与HBsAg或抗体的存在以及黄疸病史有关。不同组患者之间无显著差异。