Inaba N, Ohkawa R, Matsuura A, Kudoh J, Takamizawa H
Br J Vener Dis. 1979 Oct;55(5):366-8. doi: 10.1136/sti.55.5.366.
The husbands of 68 hepatitis B surface antigen (HBsAg) carrier-state wives were tested for the presence of hepatitis B surface antibody (HBsAb) and antigen (HBsAg) to assess possible transmission of HBsAg. Eight (11.8%) of the 68 husbands gave negative results for HBsAg and 22 (32.4%) positive results for HBsAb. Furthermore, eight (26.7%) of 30 husbands with presumed HBsAg transmission from their wives developed acute viral hepatitis after marriage, and e antigen (eAg) was detected in the serum from all eight wives. Although HbsAg was not detected in specimens of sputum and cervical mucus of carrier-state women by reverse passive haemagglutination, it was detected in the vaginal discharge of women during days 1--6 of the menstrual cycle at a rate ranging from 20--60%. Thus, sexual transmission of HBsAg seems to occur, particularly if sexual contact takes place during or immediately after menstruation.
对68名乙肝表面抗原（HBsAg）携带状态女性的丈夫进行了乙肝表面抗体（HBsAb）和抗原（HBsAg）检测，以评估HBsAg的可能传播情况。68名丈夫中，8名（11.8%）HBsAg检测结果为阴性，22名（32.4%）HBsAb检测结果为阳性。此外，30名推测从妻子处感染HBsAg的丈夫中，有8名（26.7%）婚后发生了急性病毒性肝炎，且所有8名妻子的血清中均检测到e抗原（eAg）。虽然通过反向被动血凝试验在携带状态女性的痰液和宫颈黏液标本中未检测到HbsAg，但在月经周期第1 - 6天女性的阴道分泌物中检测到了HbsAg，检出率在20% - 60%之间。因此，HBsAg似乎可通过性传播，尤其是在月经期间或月经刚结束后发生性接触时。
