小儿年龄组非血液系统肿瘤的细针穿刺细胞学检查：我们的经验

Fine needle aspiration cytology of non-hematological neoplasms in pediatric age group: Our experience.

作者信息

Gangopadhyay Mimi, Chakrabarti Indranil, Ghosh Piyali, Ghosh Nilanjana, Sinha Mamata Guha Mallick

机构信息

Department of Pathology, North Bengal Medical College, Sushrutanagar, Darjeeling, West Bengal, India.

Department of Community Medicine, North Bengal Medical College, Sushrutanagar, Darjeeling, West Bengal, India.

出版信息

J Cytol. 2015 Jul-Sep;32(3):165-9. doi: 10.4103/0970-9371.168841.

DOI:10.4103/0970-9371.168841

PMID:26729976

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4687206/

Abstract

BACKGROUND

The role of aspiration cytology has largely been ignored in pediatric population. The present study was undertaken to evaluate the role of fine needle aspiration cytology (FNAC) in non-hematological neoplasms in children in our institution, which is a rural tertiary care center.

MATERIALS AND METHODS

A total of 88 cases of non-hematological pediatric mass lesions were studied in which cytopathological diagnosis could be corroborated with histopathology.

RESULTS

Out of all the cases, 70 (80%) cases were benign tumors and 18 (20%) were malignant tumors. Fibroadenoma (37.9%) comprised the majority of cases in the benign category while small round cell tumors (SRCTs) (44.4%) comprised the majority of cases in the malignant category. Definite diagnosis could be offered based on the cytomorphology in 79.5% cases, while in 20.5% of cases only a broad cytological classification could be offered. Among the malignant lesions, FNAC showed 100% sensitivity while a specific diagnosis was made in 90% of cases.

CONCLUSION

FNAC proved to be a rapid and fairly accurate tool in diagnosing non-hematological tumors in the pediatric age group.

摘要

背景

细针穿刺细胞学检查在儿科人群中的作用在很大程度上被忽视了。本研究旨在评估细针穿刺细胞学检查（FNAC）在我院（一家农村三级医疗中心）儿童非血液系统肿瘤中的作用。

材料与方法

共研究了88例儿童非血液系统肿块病变，其细胞病理学诊断可与组织病理学相互印证。

结果

在所有病例中，70例（80%）为良性肿瘤，18例（20%）为恶性肿瘤。纤维腺瘤（37.9%）在良性肿瘤类别中占大多数，而小圆细胞肿瘤（SRCTs）（44.4%）在恶性肿瘤类别中占大多数。79.5%的病例可根据细胞形态学做出明确诊断，而20.5%的病例只能给出大致的细胞学分类。在恶性病变中，FNAC的敏感性为100%，90%的病例做出了明确诊断。