Agrawal Ranjan, Garg Cheena, Agarwal Arjun, Kumar Parbodh
Department of Pathology, Rohilkhand Medical College Hospital, Bareilly, Uttar Pradesh, India.
J Cytol. 2015 Jul-Sep;32(3):194-6. doi: 10.4103/0970-9371.168899.
Primary apocrine sweat gland adenocarcinomas are a rare entity, with only a few case reports so far. Many of these carcinomas are slow-growing with a high recurrence rate. A distinct cytological diagnosis can be made, and metastatic adenocarcinomas are always considered as a differential diagnosis on cytology. Our case was a 35-year-old male who presented with a discharging axillary sinus and swelling for the past 1 year. A clinical suspicion of tuberculous sinus was raised that however, remained unsupported by laboratory investigations. There was quite a high suspicion of apocrine adenocarcinoma on cytological examination that was confirmed by histopathology and immunohistochemistry. The patient was successfully treated with total excision and a wide margin. We report this case in view of its rarity and its occurrence in a 35-year-old young male, and emphasize that an initial cytological suspicion should be raised for primary apocrine adenocarcinoma in case of an axillary tumor, especially keeping in consideration the poor prognosis of the same and chances of early metastasis.
原发性大汗腺腺癌是一种罕见的疾病,迄今为止仅有少数病例报告。这些癌中的许多生长缓慢,但复发率高。可以做出明确的细胞学诊断,转移性腺癌在细胞学上始终被视为鉴别诊断。我们的病例是一名35岁男性,过去1年来出现腋窝窦道排液和肿胀。临床上怀疑是结核性窦道,但实验室检查未予支持。细胞学检查高度怀疑为大汗腺腺癌,经组织病理学和免疫组化证实。患者通过完整切除及宽切缘成功治愈。鉴于该病例的罕见性及其发生在一名35岁年轻男性身上,我们报告此病例,并强调对于腋窝肿瘤,尤其是考虑到原发性大汗腺腺癌预后不良及早期转移的可能性,应首先从细胞学上怀疑原发性大汗腺腺癌。