Suppr超能文献

临床路径在胃癌腹腔镜胃切除术中的应用。

Use of a clinical pathway in laparoscopic gastrectomy for gastric cancer.

作者信息

Kim Hee Sung, Kim Sun Oak, Kim Byung Sik

机构信息

Hee Sung Kim, Byung Sik Kim, Department of Gastric Surgery, Asan Medical Center, Ulsan University School of Medicine, Seoul 138-736, South Korea.

出版信息

World J Gastroenterol. 2015 Dec 28;21(48):13507-17. doi: 10.3748/wjg.v21.i48.13507.

Abstract

AIM

To evaluate the implementation of a clinical pathway and identify clinical factors affecting the clinical pathway for laparoscopic gastrectomy.

METHODS

A standardized clinical pathway for gastric cancer (GC) patients was developed in 2001 by the GC surgery team at the Asan Medical Center. We reviewed the collected data of 4800 consecutive patients treated using the clinical pathway following laparoscopic gastrectomy with lymph node dissection for GC involving intracorporeal and extracorporeal anastomosis. The patients were treated between August 2004 and October 2013 in a single institution. To evaluate the rate of completion and risk factors affecting dropout from the clinical pathway, we used a multivariate logistic regression analysis.

RESULTS

The overall completion rate of the clinical pathway for laparoscopic gastrectomy was 84.1% (n = 4038). In the comparison between groups of intracorporeal anastomosis and extracorporeal anastomosis patients, the completion rates were 83.88% (n = 1740) and 84.36% (n = 2071), respectively, showing no statistically significant difference. The main reasons for dropping out were postoperative complications (n = 463, 9.7%) and the need for patient observation (n = 299, 6.2%). Among the discharged patients treated using the clinical pathway, the number of patients who were readmitted within 30 d due to postoperative complications was 54 (1.1%). In a multivariate analysis, the intraoperative events (OR = 2.558) were the most predictable risk factors for dropping out of the clinical pathway. Additionally, being male (OR = 1.459), advanced age (OR = 1.727), total gastrectomy (OR = 2.444), combined operation (OR = 1.731), and ASA score (OR = 1.889) were significant risk factors affecting the dropout rate from the clinical pathway.

CONCLUSION

Laparoscopic gastrectomy appears to be a good indication for the application of a clinical pathway. For successful application, patients with risk factors should be managed carefully.

摘要

目的

评估临床路径的实施情况,并确定影响腹腔镜胃切除术临床路径的临床因素。

方法

2001年,峨山医学中心的胃癌手术团队制定了标准化的胃癌(GC)患者临床路径。我们回顾了4800例连续接受腹腔镜胃切除术加淋巴结清扫术治疗GC(包括体内和体外吻合)的患者的收集数据,这些患者于2004年8月至2013年10月在单一机构接受治疗。为了评估临床路径的完成率和影响退出临床路径的危险因素,我们使用了多因素逻辑回归分析。

结果

腹腔镜胃切除术临床路径的总体完成率为84.1%(n = 4038)。在体内吻合组和体外吻合组患者的比较中,完成率分别为83.88%(n = 1740)和84.36%(n = 2071),无统计学显著差异。退出的主要原因是术后并发症(n = 463,9.7%)和需要对患者进行观察(n = 299,6.2%)。在使用临床路径治疗的出院患者中,因术后并发症在30天内再次入院的患者有54例(1.1%)。在多因素分析中,术中事件(OR = 2.558)是退出临床路径最可预测的危险因素。此外,男性(OR = 1.459)、高龄(OR = 1.727)、全胃切除术(OR = 2.444)、联合手术(OR = 1.731)和美国麻醉医师协会(ASA)评分(OR = 1.889)是影响临床路径退出率的显著危险因素。

结论

腹腔镜胃切除术似乎是临床路径应用的良好适应证。为成功应用,应谨慎管理有危险因素的患者。

相似文献

1
Use of a clinical pathway in laparoscopic gastrectomy for gastric cancer.
World J Gastroenterol. 2015 Dec 28;21(48):13507-17. doi: 10.3748/wjg.v21.i48.13507.
8
Laparoscopic vs open D2 gastrectomy for locally advanced gastric cancer: a meta-analysis.
World J Gastroenterol. 2014 Nov 28;20(44):16750-64. doi: 10.3748/wjg.v20.i44.16750.

本文引用的文献

3
Management of gastric cancer in Asia: resource-stratified guidelines.
Lancet Oncol. 2013 Nov;14(12):e535-47. doi: 10.1016/S1470-2045(13)70436-4.
5
Sex dimorphism and depot differences in adipose tissue function.
Biochim Biophys Acta. 2014 Mar;1842(3):377-92. doi: 10.1016/j.bbadis.2013.05.006. Epub 2013 May 16.
6
Comparison of totally laparoscopic total gastrectomy and open total gastrectomy for gastric cancer.
J Laparoendosc Adv Surg Tech A. 2013 Apr;23(4):323-31. doi: 10.1089/lap.2012.0389. Epub 2013 Feb 4.
9
Totally laparoscopic total gastrectomy using endoscopic linear stapler: early experiences at one institute.
J Laparoendosc Adv Surg Tech A. 2012 Nov;22(9):889-97. doi: 10.1089/lap.2012.0238.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验