Department of Medicine, Washington University in St Louis School of Medicine, St Louis, MO, USA.
Department of Surgery, Washington University in St Louis School of Medicine, St Louis, MO, USA.
Breast Cancer (Dove Med Press). 2015 Dec 21;8:1-12. doi: 10.2147/BCTT.S68848. eCollection 2016.
Breast cancer in young women is relatively rare compared to breast cancer occurring in older women. Younger women diagnosed with breast cancer also tend to have a more aggressive biology and consequently a poorer prognosis than older women. In addition, they face unique challenges such as diminished fertility from premature ovarian failure, extended survivorship periods and its attendant problems, and the psychosocial impact of diagnosis, while still raising families. It is therefore imperative to recognize the unique issues that younger women face, and plan management in a multidisciplinary fashion to optimize clinical outcomes. This paper discusses the challenges of breast cancer management for young women, as well as specific issues to consider in diagnosis, treatment, and follow-up of such patients.
与老年女性相比,年轻女性的乳腺癌相对较少。年轻女性被诊断出患有乳腺癌,其生物学特性往往更具侵袭性,因此预后比老年女性差。此外,她们还面临着独特的挑战,如因卵巢早衰导致生育能力下降、延长的生存时间及其伴随的问题,以及诊断后的心理社会影响,同时仍要抚养家庭。因此,必须认识到年轻女性面临的独特问题,并以多学科的方式规划管理,以优化临床结果。本文讨论了年轻女性乳腺癌管理的挑战,以及在这些患者的诊断、治疗和随访中需要考虑的具体问题。