Xiao Hui, Ghazinour Golnaz, Tabaczynski Allyson, Chong Sum Yi, Koperwas Ina, Trinh Linda
Faculty of Kinesiology and Physical Education, University of Toronto, 55 Harbord Street, Toronto, ON, M5S 2W6, Canada.
J Cancer Surviv. 2025 Apr 21. doi: 10.1007/s11764-025-01810-8.
This study aimed to identify distinct profiles of quality of life (QoL) and lifestyle behaviors among cancer survivors and explore their associations with clinical and demographic factors.
A cross-sectional survey was conducted globally from July to November 2020 among cancer survivors aged 18 and older. Sedentary behavior and sleep were assessed using a modified Domain-Specific Sitting Time Questionnaire, physical activity with the Godin Leisure-Time Exercise Questionnaire, and QoL via the Functional Assessment of Cancer Therapy scale. Latent profile analysis identified subgroups based on lifestyle behaviors, and multinomial logistic regression examined clinical and demographic associations.
Among 477 cancer survivors (Mage = 48.5 ± 15.4 years), predominantly female (69.6%) and diagnosed with breast cancer (29.3%), three latent profiles were identified: Class 1 ("Limited 24-Hour Movement with Low Well-being"), Class 2 ("Partial 24-Hour Movement with Moderate Well-being"), and Class 3 ("Complete 24-Hour Movement with High Well-being"). Class 3 had the highest physical activity, lowest sedentary time, and best QoL, associated with older age, lower body mass index, fewer comorbidities, and less chemotherapy or hormone therapy.
Identifying latent profiles of QoL and lifestyle behaviors highlights opportunities for tailored interventions in cancer survivorship care.
Survivors in low well-being profiles may benefit from targeted interventions to reduce sedentary behavior, increase physical activity, and address fatigue and comorbidities. Those in high well-being profiles may need support to sustain healthy habits and manage emotional well-being.
本研究旨在确定癌症幸存者的不同生活质量（QoL）和生活方式行为特征，并探讨它们与临床和人口统计学因素之间的关联。
2020年7月至11月在全球范围内对18岁及以上的癌症幸存者进行了一项横断面调查。使用改良的特定领域久坐时间问卷评估久坐行为和睡眠，使用戈丁休闲时间运动问卷评估身体活动，并通过癌症治疗功能评估量表评估生活质量。潜在剖面分析根据生活方式行为确定亚组，多项逻辑回归分析临床和人口统计学关联。
在477名癌症幸存者（年龄中位数=48.5±15.4岁）中，以女性为主（69.6%），主要诊断为乳腺癌（29.3%），确定了三个潜在剖面：第1类（“24小时活动受限且幸福感低”）、第2类（“24小时部分活动且幸福感中等”）和第3类（“24小时完全活动且幸福感高”）。第3类身体活动水平最高，久坐时间最短，生活质量最佳，与年龄较大、体重指数较低、合并症较少以及化疗或激素治疗较少有关。
确定生活质量和生活方式行为的潜在剖面突出了在癌症幸存者护理中进行针对性干预的机会。
幸福感较低剖面的幸存者可能受益于有针对性的干预措施，以减少久坐行为、增加身体活动，并解决疲劳和合并症问题。幸福感较高剖面的幸存者可能需要支持以维持健康习惯并管理情绪健康。
