Identifying latent profiles of quality of life and lifestyle behaviors in cancer survivors: The interplay of sedentary behavior, physical activity, and sleep.

PURPOSE

This study aimed to identify distinct profiles of quality of life (QoL) and lifestyle behaviors among cancer survivors and explore their associations with clinical and demographic factors.

METHODS

A cross-sectional survey was conducted globally from July to November 2020 among cancer survivors aged 18 and older. Sedentary behavior and sleep were assessed using a modified Domain-Specific Sitting Time Questionnaire, physical activity with the Godin Leisure-Time Exercise Questionnaire, and QoL via the Functional Assessment of Cancer Therapy scale. Latent profile analysis identified subgroups based on lifestyle behaviors, and multinomial logistic regression examined clinical and demographic associations.

RESULTS

Among 477 cancer survivors (Mage = 48.5 ± 15.4 years), predominantly female (69.6%) and diagnosed with breast cancer (29.3%), three latent profiles were identified: Class 1 ("Limited 24-Hour Movement with Low Well-being"), Class 2 ("Partial 24-Hour Movement with Moderate Well-being"), and Class 3 ("Complete 24-Hour Movement with High Well-being"). Class 3 had the highest physical activity, lowest sedentary time, and best QoL, associated with older age, lower body mass index, fewer comorbidities, and less chemotherapy or hormone therapy.

CONCLUSIONS

Identifying latent profiles of QoL and lifestyle behaviors highlights opportunities for tailored interventions in cancer survivorship care.

IMPLICATIONS FOR CANCER SURVIVORS

Survivors in low well-being profiles may benefit from targeted interventions to reduce sedentary behavior, increase physical activity, and address fatigue and comorbidities. Those in high well-being profiles may need support to sustain healthy habits and manage emotional well-being.