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门静脉高压症中直肠静脉曲张的管理

Management of rectal varices in portal hypertension.

作者信息

Al Khalloufi Kawtar, Laiyemo Adeyinka O

机构信息

Kawtar Al Khalloufi, Adeyinka O Laiyemo, Division of Gastroenterology, Department of Medicine, Howard University College of Medicine, Washington, DC 20060, United States.

出版信息

World J Hepatol. 2015 Dec 28;7(30):2992-8. doi: 10.4254/wjh.v7.i30.2992.

Abstract

Rectal varices are portosystemic collaterals that form as a complication of portal hypertension, their prevalence has been reported as high as 94% in patients with extrahepatic portal vein obstruction. The diagnosis is typically based on lower endoscopy (colonoscopy or sigmoidoscopy). However, endoscopic ultrasonography has been shown to be superior to endoscopy in diagnosing rectal varices. Color Doppler ultrasonography is a better method because it allows the calculation of the velocity of blood flow in the varices and can be used to predict the bleeding risk in the varices. Although rare, bleeding from rectal varices can be life threatening. The management of patients with rectal variceal bleeding is not well established. It is important to ensure hemodynamic stability with blood transfusion and to correct any coagulopathy prior to treating the bleeding varices. Endoscopic injection sclerotherapy has been reported to be more effective in the management of active bleeding from rectal varices with less rebleeding rate as compared to endoscopic band ligation. Transjugular intrahepatic portsystemic shunt alone or in combination with embolization is another method used successfully in control of bleeding. Balloon-occluded retrograde transvenous obliteration is an emerging procedure for management of gastric varices that has also been successfully used to treat bleeding rectal varices. Surgical procedures including suture ligation and porto-caval shunts are considered when other methods have failed.

摘要

直肠静脉曲张是门静脉高压并发症所形成的门体静脉侧支循环,据报道,在肝外门静脉阻塞患者中其患病率高达94%。诊断通常基于下消化道内镜检查(结肠镜检查或乙状结肠镜检查)。然而,内镜超声检查在诊断直肠静脉曲张方面已被证明优于内镜检查。彩色多普勒超声检查是一种更好的方法,因为它可以计算静脉曲张内的血流速度,并可用于预测静脉曲张的出血风险。尽管直肠静脉曲张出血很少见,但可能危及生命。直肠静脉曲张出血患者的治疗方法尚未完全确立。在治疗出血的静脉曲张之前,通过输血确保血流动力学稳定并纠正任何凝血功能障碍很重要。据报道,与内镜下套扎术相比,内镜注射硬化疗法在治疗直肠静脉曲张活动性出血方面更有效,再出血率更低。经颈静脉肝内门体分流术单独或联合栓塞术是另一种成功用于控制出血的方法。球囊闭塞逆行静脉栓塞术是一种新兴的治疗胃静脉曲张的方法,也已成功用于治疗出血性直肠静脉曲张。当其他方法失败时,考虑包括缝合结扎和门腔分流术在内的外科手术。

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