Chaudhuri Urmimala, Casini Diane S, Prince Sean-Patrick A, Agrawal Sangeeta
Internal Medicine Residency Program, Wright State University, Dayton, USA.
Internal Medicine, Wright State University/Premier Health, Dayton, USA.
Cureus. 2025 May 18;17(5):e84339. doi: 10.7759/cureus.84339. eCollection 2025 May.
Rectal varices (RV) are portosystemic collaterals that are a result of portal hypertension. RV prevalence has been reported between 63% and 94% among patients with cirrhosis; however, clinically significant bleeding is a rare complication and occurs in about 0.5% to 5% of patients. To date, no specific evidence-based guidelines exist for the management of bleeding RV, which can be life-threatening with a high morbidity and mortality. Current management involves a multidisciplinary team and urgent endoscopic evaluation in all patients. Here, we present a rare case of severe RV bleeding in a patient with cirrhosis presumed secondary to alcohol use, who ultimately expired despite multiple endoscopic interventions and salvage therapies. The patient's deteriorating condition from severe hemorrhagic shock and limitation of procedures given poor candidacy for transjugular intrahepatic portosystemic shunt (TIPS) highlights the limited treatment options available in such advanced cases. It warrants further discussions on establishing dedicated guidelines and advancing therapies for refractory cases.
直肠静脉曲张(RV)是门体分流支,由门静脉高压引起。据报道,肝硬化患者中RV的患病率在63%至94%之间;然而,具有临床意义的出血是一种罕见的并发症,约0.5%至5%的患者会发生。迄今为止,尚无针对出血性RV管理的具体循证指南,出血性RV可能危及生命,发病率和死亡率都很高。目前的管理需要多学科团队参与,所有患者都要进行紧急内镜评估。在此,我们报告一例罕见的严重RV出血病例,患者为一名推测因饮酒继发肝硬化的患者,尽管进行了多次内镜干预和挽救治疗,最终仍死亡。患者因严重失血性休克病情恶化以及经颈静脉肝内门体分流术(TIPS)候选资格不佳而限制了手术,这突出了此类晚期病例可用治疗选择的有限性。有必要进一步讨论制定专门的指南以及推进针对难治性病例的治疗方法。