Meldrum David R
Reproductive Partners La Jolla, La Jolla, California; Division of Reproductive Endocrinology and Infertility, Department of Reproductive Medicine, University of California at San Diego, San Diego, California.
Fertil Steril. 2016 Mar;105(3):545-547. doi: 10.1016/j.fertnstert.2015.12.007. Epub 2015 Dec 28.
The environment of the oocyte and embryo includes the metabolic effects of aging, lifestyle issues, psychological stress, nutritional supplements/replacements, cellular energy levels, endocrine and paracrine factors, the cumulus, exogenous gonadotropins and adjunctive medications, culture media, and the in vitro fertilization laboratory's conditions and manipulations. These complex factors, which will be examined in the following series of reviews, explain in part why not all euploid blastocysts result in viable pregnancies.
卵母细胞和胚胎的环境包括衰老的代谢影响、生活方式问题、心理压力、营养补充剂/替代物、细胞能量水平、内分泌和旁分泌因子、卵丘、外源性促性腺激素和辅助药物、培养基以及体外受精实验室的条件和操作。这些复杂因素将在以下一系列综述中进行探讨，部分解释了为什么并非所有整倍体囊胚都能导致活产妊娠。
