Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad mixta Universitat Politècnica de València-Universitat de València , Camino de Vera s/n, 46022 València, Spain.
CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN).
Chem Rev. 2016 Jan 27;116(2):561-718. doi: 10.1021/acs.chemrev.5b00456. Epub 2016 Jan 5.
Multidisciplinary research at the forefront of the field of hybrid materials has paved the way to the development of endless examples of smart devices. One appealing concept in this fertile field is related to the design of gated materials. These are constructed for finely tuning the delivery of chemical or biochemical species from voids of porous supports to a solution in response to predefined stimuli. Such gated materials are composed mainly of two subunits: (i) a porous inorganic support in which a cargo is loaded and (ii) certain molecular or supramolecular entities, generally grafted onto the external surface, which can control mass transport from pores. On the basis of this concept, a large number of imaginative examples have been developed. This review intends to be a comprehensive analysis of papers published until 2014 on hybrid mesoporous gated materials. The molecules used as gates, the opening mechanisms, and controlled release behavior are detailed. We hope this review will not only help researchers who work in this field but also may open the minds of related ones to develop new advances in this fertile research area.
多学科研究处于混合材料领域的前沿，为开发无数智能设备铺平了道路。在这个多产领域中，一个吸引人的概念与门控材料的设计有关。这些材料的设计目的是精细调节从多孔载体的空隙到溶液中化学或生物化学物质的传递，以响应预定的刺激。这种门控材料主要由两个亚单位组成：(i)多孔无机载体，其中负载有货物，以及(ii)通常接枝在外部表面上的某些分子或超分子实体，它们可以控制从孔中传输质量。基于这个概念，已经开发出了大量富有想象力的例子。这篇综述旨在对 2014 年之前发表的关于混合介孔门控材料的论文进行全面分析。详细介绍了用作门的分子、开启机制和控制释放行为。我们希望这篇综述不仅能帮助该领域的研究人员，而且还能启发相关人员在这个富有成效的研究领域取得新的进展。
