Boarbi Samira, Fretin David, Mori Marcella
Centre d'étude et de recherches vétérinaires et agrochimiques (CERVA), Direction opérationnelle des maladies bactériennes, Zoonoses bactériennes des animaux de rente, Groeselenberg 99, 1180 Bruxelles, Belgique.
Can J Microbiol. 2016 Feb;62(2):102-22. doi: 10.1139/cjm-2015-0551. Epub 2015 Nov 5.
Q fever is a zoonosis of worldwide distribution with the exception of New Zealand. It is caused by an intracellular bacterium, Coxiella burnetii. The disease often goes underdiagnosed because the main manifestation of its acute form is a general self-limiting flu-like syndrome. The Dutch epidemics renewed attention to this disease, which was less considered before. This review summarizes the description of C. burnetii (taxonomy, intracellular cycle, and genome) and Q fever disease (description, diagnosis, epidemiology, and pathogenesis). Finally, vaccination in humans and animals is also considered.
Q热是一种除新西兰外全球均有分布的人畜共患病。它由细胞内细菌伯氏考克斯氏体引起。该疾病常被漏诊，因为其急性形式的主要表现是一种具有自限性的类似流感的综合征。荷兰的疫情重新引起了对这种此前较少受到关注的疾病的重视。本综述总结了伯氏考克斯氏体的描述（分类学、细胞内周期和基因组）以及Q热疾病（描述、诊断、流行病学和发病机制）。最后，还考虑了人类和动物的疫苗接种情况。
