Kay E B
Department of Cardiovascular Surgery, St. Vincent Charity Hospital, Cleveland, Ohio.
Ann Thorac Surg. 1989 Sep;48(3 Suppl):S24-5. doi: 10.1016/0003-4975(89)90625-5.
Various types of prosthetic heart valves developed and tested in the laboratory beginning in 1958 are described. Seven of such valves were implanted clinically in patients with congestive heart failure previously operated on by both the closed and open techniques in 1958 and 1959. The longest survivor was 6 weeks. Evidence is presented demonstrating that putting a film of polyurethane on the Teflon leaflet valve and fixation rings of disc valves reduces thrombosis, thromboembolism, and tissue overgrowth interfering with disc or ball valve function.
本文描述了自1958年起在实验室研发和测试的各类人工心脏瓣膜。1958年和1959年，其中7种瓣膜被临床植入充血性心力衰竭患者体内，这些患者此前已接受过闭式和开式手术。最长存活时间为6周。有证据表明，在聚四氟乙烯瓣叶瓣膜和盘状瓣膜的固定环上覆盖一层聚氨酯薄膜可减少血栓形成、血栓栓塞以及干扰盘状或球瓣功能的组织过度生长。
