Kistler H J, Plüer S, Dickenmann W, Pirozynski W
Schweiz Med Wochenschr. 1977 Jun 18;107(24):825-32.
The ysmptoms and findings in a patient after prolonged intake of excessive amounts of vitamin A for treatment of psoriasis are presentd. All the characteristic signs of chronic intoxication were reversible after withdrawal of the medication. Initially portal hypertension could be demonstrated, although histologically there was no cirrhosis of the liver. During the period of observation the disturbed liver function returned to normal and the signs of portal hypertension disappeared completely. Reversibility of portal hypertension is a unusual observation and is discussed in relation to similar situations in toxic liver disease.
本文呈现了一名患者因长期过量摄入维生素A治疗银屑病后的症状和检查结果。停药后，所有慢性中毒的特征性体征均可逆。最初可证实存在门静脉高压，尽管组织学检查未发现肝硬化。在观察期间，肝功能紊乱恢复正常，门静脉高压体征完全消失。门静脉高压的可逆性是一项不寻常的观察结果，并结合中毒性肝病的类似情况进行了讨论。
