Inceu Georgeta Victoria, Veresiu Ioan Andrei
Department of Diabetes, , Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Clujul Med. 2015;88(4):449-52. doi: 10.15386/cjmed-491. Epub 2015 Nov 15.
The incidence of diabetes mellitus is continuously growing worldwide, while the specific chronic complications that it induces have a negative impact on life expectancy andquality, entailing extremely high costs of healthcare services. Diabetic peripheral neuropathy is one of the most common chronic complications of diabetes, affecting almost half of diabetic people during life. This review aims at summarizing the evidence on the advantages and the usefulness of current perception threshold measurement for peripheral diabetic neuropathy assessment. Among the different methods used for the screening and diagnosis of diabetic neuropathy, measurement of current perception threshold using the Neurometer® has the ability to assess three sub-types of nerve fiber by producing transcutaneous electrical stimuli at frequencies of 2000, 250 and 5 Hz. Current evidence shows that this method provides a useful, noninvasive evaluation technique of patients with peripheral nervous system disorders, being able to detect neuropathy in the earliest and asymptomatic stages.
全球范围内,糖尿病的发病率持续上升,而其所引发的特定慢性并发症会对预期寿命和生活质量产生负面影响,导致医疗服务成本极高。糖尿病周围神经病变是糖尿病最常见的慢性并发症之一,几乎一半的糖尿病患者在其病程中会受到影响。本综述旨在总结当前关于感觉阈值测量在评估糖尿病周围神经病变方面的优势及实用性的证据。在用于筛查和诊断糖尿病神经病变的不同方法中,使用神经传导速度测量仪(Neurometer®)测量电流感觉阈值,能够通过以2000、250和5赫兹的频率产生经皮电刺激来评估三种神经纤维亚型。目前的证据表明,该方法为患有周围神经系统疾病的患者提供了一种有用的非侵入性评估技术,能够在最早的无症状阶段检测出神经病变。