微小RNA作为结直肠癌的非侵入性筛查生物标志物
MicroRNAs as non-invasive screening biomarkers of colorectal cancer.
作者信息
Saplacan Roberta Maria Manzat, Mircea Petru Adrian, Balacescu Loredana, Balacescu Ovidiu
机构信息
Department of Internal Medicine, 1st Medical Clinic, Cluj-Napoca, Iuliu Hatieganu University of Medicine and Pharmacy Cluj-Napoca, Romania.
Department of Functional Genomics, Proteomics and Experimental Pathology, Prof. Dr. Ion Chiricuta Oncology Institute, Cluj-Napoca, Romania.
出版信息
Clujul Med. 2015;88(4):453-6. doi: 10.15386/cjmed-568. Epub 2015 Nov 15.
Abstract
Colorectal cancer is a major cause of cancer-associated deaths in the world. Early detection would be greatly enhanced if accurate and cost-effective diagnostic biomarkers for this disease were accessible. The development of such a blood test will evidently lower the screening costs in regards of colorectal cancer detection. Lately, it has been suggested that microRNA diagnostic biomarkers are feasible new screening methods for colorectal cancer. This review summarizes the diagnostic potential of circulating microRNA biomarkers in relation with colorectal cancer, as well as current methods to detect them.
摘要
结直肠癌是全球癌症相关死亡的主要原因之一。如果能够获得针对该疾病准确且具有成本效益的诊断生物标志物，早期检测将得到极大加强。这种血液检测的开发显然会降低结直肠癌检测的筛查成本。最近，有人提出微小RNA诊断生物标志物是结直肠癌可行的新筛查方法。本综述总结了循环微小RNA生物标志物在结直肠癌诊断中的潜力，以及目前检测它们的方法。
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J Exp Clin Cancer Res. 2015 Aug 22;34(1):86. doi: 10.1186/s13046-015-0198-6.
2
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Asian Pac J Cancer Prev. 2015;16(13):5163-7. doi: 10.7314/apjcp.2015.16.13.5163.
3
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Cancer Epidemiol Biomarkers Prev. 2015 Sep;24(9):1373-80. doi: 10.1158/1055-9965.EPI-15-0085. Epub 2015 Jun 16.
4
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5
Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study.评价定量 miRNA 表达平台在 microRNA 质量控制（miRQC）研究中的应用。
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6
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7
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