通过碘化亚铜催化的分子内N-芳基化反应简洁高效地合成苯并咪唑并[1,2-c]喹唑啉类化合物。
A concise and efficient synthesis of benzimidazo[1,2-c]quinazolines through CuI-catalyzed intramolecular N-arylations.
作者信息
Pang Xinlong, Chen Chao, Li Ming, Xi Chanjuan
机构信息
Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China, Tel: +86-10-62773684; College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China.
Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, China, Tel: +86-10-62773684.
出版信息
Beilstein J Org Chem. 2015 Nov 30;11:2365-9. doi: 10.3762/bjoc.11.258. eCollection 2015.
A series of functionalized benzimidazo[1,2-c]quinazoline derivatives was obtained in excellent yields under mild conditions through a CuI-catalyzed Ullmann N-arylation starting from easily available starting materials.
通过铜催化的乌尔曼N-芳基化反应，以易于获得的起始原料为基础，在温和条件下以优异的产率得到了一系列功能化的苯并咪唑并[1,2-c]喹唑啉衍生物。
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