过氧化氢酶与脑乙醛的产生：乙醇心理药理作用的一种可能介质。
Catalase and the production of brain acetaldehyde: a possible mediator of the psychopharmacological effects of ethanol.
作者信息
Smith B R, Aragon C M, Amit Z
机构信息
Center for Studies in Behavioral Neurobiology, Concordia University, Montreal, Canada.
出版信息
Addict Biol. 1997 Jul;2(3):277-90. doi: 10.1080/13556219772570.
This review represents an attempt to assess the available data on the role of catalase in the mediation of the behavioral actions of ethanol and the regulation of voluntary ethanol consumption. It is argued that acetaldehyde may be formed in brain through the peroxidatic activity of catalase. Furthermore, acetaldehyde formed centrally through the activity of this enzyme, may be responsible, at least in part, for some of the motivational, behavioral and neurotoxic effects of ethanol.
本综述旨在评估过氧化氢酶在介导乙醇行为作用及调节自愿乙醇摄入方面的现有数据。有人认为，乙醛可能通过过氧化氢酶的过氧化物酶活性在大脑中形成。此外，通过该酶的活性在中枢形成的乙醛可能至少部分地导致了乙醇的一些动机、行为和神经毒性作用。
Zotero 插件