Kerr Jacqueline, Takemoto Michelle, Bolling Khalisa, Atkin Andrew, Carlson Jordan, Rosenberg Dori, Crist Katie, Godbole Suneeta, Lewars Brittany, Pena Claudia, Merchant Gina
Department of Family Medicine and Public Health, University of California, San Diego, California, United States of America.
UKCRC Centre for Diet and Activity Research (CEDAR), University of Cambridge School of Clinical Medicine, CB2 0QQ, United Kingdom.
PLoS One. 2016 Jan 6;11(1):e0145427. doi: 10.1371/journal.pone.0145427. eCollection 2016.
Excessive sitting has been linked to poor health. It is unknown whether reducing total sitting time or increasing brief sit-to-stand transitions is more beneficial. We conducted a randomized pilot study to assess whether it is feasible for working and non-working older adults to reduce these two different behavioral targets.
Thirty adults (15 workers and 15 non-workers) age 50-70 years were randomized to one of two conditions (a 2-hour reduction in daily sitting or accumulating 30 additional brief sit-to-stand transitions per day). Sitting time, standing time, sit-to-stand transitions and stepping were assessed by a thigh worn inclinometer (activPAL). Participants were assessed for 7 days at baseline and followed while the intervention was delivered (2 weeks). Mixed effects regression analyses adjusted for days within participants, device wear time, and employment status. Time by condition interactions were investigated.
Recruitment, assessments, and intervention delivery were feasible. The 'reduce sitting' group reduced their sitting by two hours, the 'increase sit-to-stand' group had no change in sitting time (p < .001). The sit-to-stand transition group increased their sit-to-stand transitions, the sitting group did not (p < .001).
This study was the first to demonstrate the feasibility and preliminary efficacy of specific sedentary behavioral goals.
clinicaltrials.gov NCT02544867.
久坐与健康状况不佳有关。目前尚不清楚减少总久坐时间或增加短暂的坐立转换是否更有益。我们进行了一项随机试点研究，以评估在职和非在职老年人减少这两个不同行为目标是否可行。
30名年龄在50 - 70岁的成年人（15名在职人员和15名非在职人员）被随机分为两种情况之一（每天减少2小时的久坐时间或每天额外增加30次短暂的坐立转换）。使用佩戴在大腿上的倾角仪（activPAL）评估久坐时间、站立时间、坐立转换次数和步数。在基线时对参与者进行7天的评估，并在实施干预期间（2周）进行跟踪。混合效应回归分析对参与者内的天数、设备佩戴时间和就业状况进行了调整。研究了情况与时间的交互作用。
招募、评估和干预实施都是可行的。“减少久坐”组的久坐时间减少了2小时，“增加坐立转换”组的久坐时间没有变化（p < 0.001）。坐立转换组的坐立转换次数增加了，久坐组则没有（p < 0.001）。
本研究首次证明了特定久坐行为目标的可行性和初步疗效。
clinicaltrials.gov NCT02544867。
