Langer P
Institute of Experimental Endocrinology, Center of Physiological Sciences, Slovak Academy of Sciences, Bratislava.
Endocrinol Exp. 1989 Jun;23(2):67-76.
The data on postmortem thyroid weight and on thyroid volume estimation with the aid of ultrasound are briefly reviewed and correlated with indicated or presumed intake of iodine in the appropriate area. The well known negative correlation between iodine intake and thyroid size may be supported even by this approach which shows that as a normal thyroid volume may be taken that obtained in areas with sufficient iodine intake such as Iceland, Sweden, Netherlands and USA. In these countries the average thyroid volume was found by various authors to be in a range of about 8 to 12 ml (or g) for females and about 11 to 15 ml (or g) in males which is approximately 10 ml (or g) less than the values considered as normal until recently. The comparisons of the data on postmortem weight or sonographically determined volume of the thyroid with palpatory findings showed that the same stage of thyroid size according to various recommended scales as found by palpation or inspection may correspond to a great variety of actual volumes and thus that the palpation may be considered as highly inaccurate method for precise estimation of thyroid size. From this view it may be recommended predominantly for large scale and low cost field epidemiological studies, while a most favourable ultrasonographic volumetry should be used for a majority of basal clinical studies and field surveys.
简要回顾了尸检甲状腺重量以及借助超声估计甲状腺体积的数据，并将其与相应地区碘的指示性摄入量或推测摄入量相关联。即使通过这种方法也可能支持碘摄入量与甲状腺大小之间众所周知的负相关关系，该方法表明可以将碘摄入充足地区（如冰岛、瑞典、荷兰和美国）所获得的甲状腺体积视为正常。在这些国家，不同作者发现女性的平均甲状腺体积约为8至12毫升（或克），男性约为11至15毫升（或克），这比直到最近仍被视为正常的值大约少10毫升（或克）。将甲状腺尸检重量或超声测定体积的数据与触诊结果进行比较表明，根据触诊或检查所发现的各种推荐标准，相同阶段的甲状腺大小可能对应于各种各样的实际体积，因此触诊可被视为精确估计甲状腺大小的高度不准确方法。从这个角度来看，它可能主要推荐用于大规模、低成本的现场流行病学研究，而对于大多数基础临床研究和现场调查，应使用最有利的超声容积测量法。
