基于拉曼散射与CMOS接触成像的实时生化传感器。

Real-time biochemical sensor based on Raman scattering with CMOS contact imaging.

作者信息

Yadid-Pecht Orly

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2015 Aug;2015:7950-3. doi: 10.1109/EMBC.2015.7320236.

DOI:10.1109/EMBC.2015.7320236

Abstract

This work presents a biochemical sensor based on Raman scattering with Complementary metal-oxide-semiconductor (CMOS) contact imaging. This biochemical optical sensor is designed for detecting the concentration of solutions. The system is built with a laser diode, an optical filter, a sample holder and a commercial CMOS sensor. The output of the system is analyzed by an image processing program. The system provides instant measurements with a resolution of 0.2 to 0.4 Mol. This low cost and easy-operated small scale system is useful in chemical, biomedical and environmental labs for quantitative bio-chemical concentration detection with results reported comparable to a highly cost commercial spectrometer.

摘要

这项工作展示了一种基于拉曼散射与互补金属氧化物半导体（CMOS）接触成像的生化传感器。这种生化光学传感器旨在检测溶液浓度。该系统由一个激光二极管、一个光学滤波器、一个样品架和一个商用CMOS传感器构建而成。系统的输出通过一个图像处理程序进行分析。该系统能够以0.2至0.4摩尔的分辨率提供即时测量结果。这种低成本且易于操作的小型系统在化学、生物医学和环境实验室中对于定量生化浓度检测很有用，其报告的结果与高成本的商用光谱仪相当。