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儿童脑室内神经鞘瘤。文献综述与病例展示。

Intraventricular schwannoma in a child. Literature review and case illustration.

作者信息

Abdolhosseinpour Hesam, Vahedi Payman, Saatian Minoo, Entezari AliReza, Narimani-Zamanabadi Mahnaz, Tubbs Richard Shane

机构信息

Department of Neurosurgery, Bouali Teaching Hospital, Tehran Medical Branch, Islamic Azad University, Tehran, Iran.

Department of Neurological Surgery, Thomas Jefferson University, Philadelphia, PA, USA.

出版信息

Childs Nerv Syst. 2016 Jun;32(6):1135-40. doi: 10.1007/s00381-015-2986-x. Epub 2016 Jan 6.

Abstract

BACKGROUND

Intraventricular schwannoma remains a rare entity in the literature. Controversy exists on the possible pathogenesis of such a tumor within cerebral ventricles. Literature is sparse on tumor characteristics and differences between pediatric and adult patients.

CASE REPORT

We present a case of intraventricular schwannoma in a 9-year-old patient presenting with headache, hemiparesis, and focal seizure. Brain CT scan and MRI revealed an intraventricular tumor within left atrium of lateral ventricle. The patient underwent total resection of the tumor via posterior parietal approach. Histopathological exam was in favor of schwannoma. Postoperative brain MRI and MRS showed no recurrence after 18 months.

CONCLUSION

Our review of the literature indicates there are some significant differences between pediatric and adult cases in different aspects including gender predominance, intraventricular location, malignant transformation, tendency for recurrence, and surgical outcome. This needs to be taken into account in the literature.

摘要

背景

脑室内神经鞘瘤在文献中仍然是一种罕见的疾病。关于这种肿瘤在脑室中的可能发病机制存在争议。关于肿瘤特征以及儿童和成人患者之间差异的文献很少。

病例报告

我们报告一例9岁脑室内神经鞘瘤患者,该患者表现为头痛、偏瘫和局灶性癫痫发作。脑部CT扫描和MRI显示侧脑室左房内有一个脑室内肿瘤。患者通过后顶叶入路接受了肿瘤全切术。组织病理学检查支持神经鞘瘤的诊断。术后18个月的脑部MRI和MRS显示无复发。

结论

我们对文献的回顾表明,儿童和成人病例在不同方面存在一些显著差异,包括性别优势、脑室内位置、恶性转化、复发倾向和手术结果。这一点在文献中需要予以考虑。

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