Sonesson B, Dias N, Resch T, Kristmundsson T, Holst J
Vascular Center Malmö-Lund, Skåne University Hospital, 205 03 Malmö, Sweden.
Vascular Center Malmö-Lund, Skåne University Hospital, 205 03 Malmö, Sweden.
Eur J Vasc Endovasc Surg. 2016 Apr;51(4):499-503. doi: 10.1016/j.ejvs.2015.11.014. Epub 2015 Dec 29.
OBJECTIVE/BACKGROUND: To evaluate if the creation of laser generated in situ fenestrations in polyester/Dacron stent grafts causes embolization.
In seven pigs, Dacron stent grafts were implanted from the infrarenal aorta to the right iliac artery. Prior to placing the stent graft, a carotid artery protection filter, with a pore size of 70-200 μm, was placed in the proximal left common iliac artery. An excimer laser catheter was then advanced antegradely through the stent graft and positioned at the level of origin of the left iliac artery. A fenestration was then created with the laser probe. The carotid filter was retrieved and inspected macroscopically with magnifying glasses, for emboli and clot.
Seven pigs with a median weight of 90 kg (range 78-98 kg) were tested. The median operating time was 170 minutes. All laser fenestrations were successfully completed. No emboli or clot could be detected in the protection filters.
Creation of laser generated, in situ fenestrations do not produce macroscopically visible emboli/clot. This might indicate safe usage of laser created fenestrations for endovascular arch repair and left subclavian artery revascularization.
目的/背景：评估在聚酯/涤纶覆膜支架移植物中激光原位开窗是否会导致栓塞。
在7头猪中，将涤纶覆膜支架移植物从肾下腹主动脉植入右髂动脉。在放置支架移植物之前，将孔径为70 - 200μm的颈动脉保护滤器置于左髂总动脉近端。然后将准分子激光导管经支架移植物向前推进并置于左髂动脉起始水平。接着用激光探头开窗。取出颈动脉滤器，用放大镜进行肉眼检查，查看有无栓子和血栓。
测试了7头猪，中位数体重为90kg（范围78 - 98kg）。中位数手术时间为170分钟。所有激光开窗均成功完成。在保护滤器中未检测到栓子或血栓。
激光原位开窗不会产生肉眼可见的栓子/血栓。这可能表明激光开窗可安全用于血管内主动脉弓修复和左锁骨下动脉血运重建。
