Broomé Michael, Donker Dirk W
School of Technology and Health, KTH Royal Institute of Technology, Alfred Nobels Allé 10, Huddinge, 141 52, Stockholm, Sweden.
ECMO Centre, Astrid Lindgren Children's Hospital, Karolinska University Hospital, 171 76, Stockholm, Sweden.
J Transl Med. 2016 Jan 6;14:4. doi: 10.1186/s12967-015-0760-1.
Veno-arterial extracoporeal membrane oxygenation (VA ECMO) is increasingly used for acute and refractory cardiogenic shock. Yet, in clinical practice, monitoring of cardiac loading conditions during VA ECMO can be cumbersome. To this end, we illustrate the validity and clinical applicability of a real-time cardiovascular computer simulation, which allows to integrate hemodynamics, cardiac dimensions and the corresponding degree of VA ECMO support and ventricular loading in individual patients over time.
静脉-动脉体外膜肺氧合(VA ECMO)越来越多地用于急性和难治性心源性休克。然而,在临床实践中,VA ECMO期间心脏负荷状况的监测可能很麻烦。为此,我们阐述了一种实时心血管计算机模拟的有效性和临床适用性,该模拟能够随时间整合个体患者的血流动力学、心脏大小以及VA ECMO支持和心室负荷的相应程度。