加拿大5家小动物诊所中与犬传染性呼吸道疾病综合征（CIRDC）发生相关的因素。
Factors associated with development of Canine Infectious Respiratory Disease Complex (CIRDC) in dogs in 5 Canadian small animal clinics.
作者信息
Joffe Daniel J, Lelewski Roxana, Weese J Scott, Mcgill-Worsley Jamie, Shankel Catharine, Mendonca Sonia, Sager Tara, Smith Michael, Poljak Zvonimir
机构信息
Associate Veterinary Clinics, Calgary, Alberta (Joffe); Department of Population Medicine (Lelewski, Poljak), Department of Pathobiology (Weese), Ontario Veterinary College, University of Guelph, Guelph, Ontario; Blue Cross Animal Clinic, Sarnia, Ontario (Mcgill-Worsley); Vancouver Animal Emergency Clinic, Vancouver, British Columbia (Shankel); Westside Veterinary Hospital, Toronto, Ontario (Mendonca); Calgary North Veterinary Hospital, Calgary, Alberta (Sager); Ottawa Veterinary Hospital, Ottawa, Ontario (Smith).
出版信息
Can Vet J. 2016 Jan;57(1):46-51.
This study investigated the association between presence of respiratory pathogens and development of Canine Infectious Respiratory Disease Complex (CIRDC) in dogs in 5 Canadian small animal clinics. In total, 86 dogs were tested using a commercial PCR respiratory panel; 64 dogs were considered as cases and 22 were control dogs matched by veterinary clinic. No control animals (0/22) were positive for canine parainfluenza virus (CPIV), whereas 27/64 (42%) CIRDC cases were positive. Furthermore, 81% of case dogs tested positive for Mycoplasma cynos, compared with 73% of control dogs. Canine respiratory corona virus (CRCoV) was detected in no control dogs compared with 9.4% of clinical dogs. No animals were positive for any influenza virus type A present in the diagnostic panel. Presence of CPIV was associated (P < 0.01) with the occurrence of CIRDC after adjustment for demographic factors and presence of CRCoV (P = 0.09).
本研究调查了加拿大5家小动物诊所中犬类呼吸道病原体的存在与犬传染性呼吸道疾病综合征（CIRDC）发生之间的关联。总共86只犬使用商业PCR呼吸道检测板进行了检测；64只犬被视为病例，22只作为对照犬，这些对照犬与病例犬来自同一兽医诊所。对照动物中无犬副流感病毒（CPIV）阳性（0/22），而CIRDC病例中有27/64（42%）呈阳性。此外，81%的病例犬检测到犬支原体呈阳性，而对照犬的这一比例为73%。对照犬中未检测到犬呼吸道冠状病毒（CRCoV），而临床病例犬中有9.4%检测到该病毒。诊断检测板中的任何甲型流感病毒均未在动物中呈阳性。在对人口统计学因素和CRCoV的存在进行调整后，CPIV的存在与CIRDC的发生相关（P<0.01），CRCoV的存在与CIRDC的发生有相关性（P = 0.09）。
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