Akdag Mehmet, Dasdag Suleyman, Ozkurt Fazil Emre, Celik Mehmet Yusuf, Degirmenci Aydin, Demir Huseyin, Meric Faruk
Department of Otolaryngology, Head & Neck Surgery, Medical School, Dicle University , Diyarbakir , Turkey.
Department of Biophysics, Medical School, Dicle University , Diyarbakir , Turkey.
Biotechnol Biotechnol Equip. 2014 Mar 4;28(2):285-294. doi: 10.1080/13102818.2014.909083. Epub 2014 Jul 10.
The aim of this retrospective study is to investigate long term (two years) effect of radiofrequency tissue volume reduction (RFVTR) on nasal obstruction associated with inferior turbinate hypertrophy, which is not respond to medical treatment. This retrospective study carried out on 98 patients with nasal obstruction treated by RFVTR (56 males, 42 females, from 17 to 70 years of age). Visual analogue scales (VAS) and nasal endoscopic view score (NES) were used for nasal obstruction to evaluate the efficacy of the treatment. Results of one, three, six, twelve and twenty four months after RFVTR treatment were compared with pre-exposure values. Turbinate edema and nasal obstruction in the treated patients were recovered after one month of treatment ( < 0.01). Maximum improvement were determined at the end of third month ( < 0.01). However, eficacy of RFVTR declined twelve months after treatment. Final percentage of imrovement was found as 51 % at the end of second year of treatment because of co-factors was not eliminated by some patients. On the other hand, no statistical significant difference was observed between the right and left nasal cavity ( < 0.001). In conclusion, the result of this study indicated that patients who have not eliminate co-factors such as smoking, obesity and allergic rhinitis may need re-application of RFTVR. However, further studies on radiofrequecy energy level and elimination of other co-factors are necessary to illuminate the eficacy of RFVTR.
这项回顾性研究的目的是调查射频组织体积减小术（RFVTR）对因下鼻甲肥大导致的药物治疗无效的鼻塞的长期（两年）效果。这项回顾性研究对98例接受RFVTR治疗的鼻塞患者进行（56例男性，42例女性，年龄17至70岁）。使用视觉模拟量表（VAS）和鼻内镜视图评分（NES）评估鼻塞情况以评价治疗效果。将RFVTR治疗后1、3、6、12和24个月的结果与治疗前的值进行比较。治疗患者的鼻甲水肿和鼻塞在治疗1个月后恢复（<0.01）。在第三个月末确定最大改善情况（<0.01）。然而，RFVTR的疗效在治疗12个月后下降。由于一些患者未消除共同因素，在治疗第二年结束时最终改善百分比为51%。另一方面，左右鼻腔之间未观察到统计学显著差异（<0.001）。总之，本研究结果表明，未消除吸烟、肥胖和变应性鼻炎等共同因素的患者可能需要再次应用RFTVR。然而，有必要对射频能量水平和消除其他共同因素进行进一步研究以阐明RFVTR的疗效。
