Venter Alina Cristiana, Roşca Elena, Daina Lucia Georgeta, Muţiu Gabriela, Pirte Adriana Nicoleta, Rahotă Daniela
Department of Neurosciences, Department of Dentistry, Faculty of Medicine and Pharmacy, University of Oradea, Romania;
Rom J Morphol Embryol. 2015;56(4):1397-402.
Phyllodes tumors are rare breast tumors, accounting for less than 1% of all primary tumors of the breast. Histologically, phyllodes tumors can be divided into benign (60%), borderline (20%) and malignant (20%). The mammography examination was performed by means of a digital mammography system Giotto 3D Images; the ultrasound examination was performed through a GE Logiq P6 device and histological confirmation was possible after surgery or following the histological biopsy. We grouped the nine patients who presented clinically palpable nodules into two groups, namely: the six patients presenting histological benign results into Group I, and Group II where we included those with borderline and malignant histological results. Mammography performed in 77.7% revealed a well-circumscribed round or oval opacity or with contour lobules. Ultrasound examination was performed in all patients. Mammography and ultrasound have limitation in differentiating between benign lesion and phyllodes tumor. In the nine analyzed cases, mammographic and ultrasound examinations did not allow the differentiation into the three groups of phyllodes tumor. Histopathological examination is considered the golden standard for their diagnosis. Correlations between mammographic and microscopic aspects were inconclusive for determining the degree of differentiation, ultrasound changes could be correlated with the histopathological aspects.
叶状肿瘤是罕见的乳腺肿瘤,占所有乳腺原发性肿瘤的比例不到1%。从组织学上看,叶状肿瘤可分为良性(60%)、交界性(20%)和恶性(20%)。乳腺钼靶检查采用Giotto 3D Images数字乳腺钼靶系统进行;超声检查通过GE Logiq P6设备进行,术后或组织活检后可进行组织学确诊。我们将9例临床上可触及结节的患者分为两组,即:6例组织学结果为良性的患者归入第一组,第二组包括组织学结果为交界性和恶性的患者。77.7%的乳腺钼靶检查显示有边界清晰的圆形或椭圆形不透光区或有分叶状轮廓。所有患者均进行了超声检查。乳腺钼靶和超声在鉴别良性病变和叶状肿瘤方面存在局限性。在分析的9例病例中,乳腺钼靶和超声检查无法将叶状肿瘤分为三组。组织病理学检查被认为是其诊断的金标准。乳腺钼靶和微观特征之间的相关性对于确定分化程度尚无定论,超声变化可与组织病理学特征相关联。