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[严重难治性艰难梭菌感染对粪便微生物群移植反应良好:一例报告]

[Severe refractory Clostridium difficile infection with good response to fecal microbiota transplantation: a case report].

作者信息

Asonuma Kunio, Kuroki Yuichiro, Ino Satoshi, Hanamura Shotaro, Takano Yuichi, Yamamura Eiichi, Gomi Kuniyo, Nagahama Masatsugu, Inoue Kazuaki, Takahashi Hiroshi

机构信息

Department of Gastroenterology, Showa University Fujigaoka Hospital.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 2016;113(1):55-62. doi: 10.11405/nisshoshi.113.55.

Abstract

A 49-year-old woman diagnosed with pseudomembranous enterocolitis was transferred to our hospital for medical treatment. She responded poorly to treatment with vancomycin hydrochloride and metronidazole, so she underwent fecal microbiota transplantation. Treatment effects were observed the next day, and the diarrhea disappeared within 3 days. Colonoscopy 4 days later revealed the resolution of pseudomembranes, and no recurrences were reported within the first year after discharge.

摘要

一名49岁被诊断为伪膜性小肠结肠炎的女性被转至我院接受治疗。她对盐酸万古霉素和甲硝唑治疗反应不佳,因此接受了粪便微生物群移植。第二天观察到治疗效果,腹泻在3天内消失。4天后的结肠镜检查显示伪膜消退,出院后第一年内未报告复发情况。

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