Forrester S D, Moreland K J
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843.
J Vet Intern Med. 1989 Jul-Sep;3(3):149-59. doi: 10.1111/j.1939-1676.1989.tb03091.x.
Severe hypophosphatemia (i.e., serum phosphorus concentration below 1 mg/dl) occurs infrequently in veterinary patients. It is most often associated with diabetic ketoacidosis in small animals. Phosphate is necessary for the production of 2,3 diphosphoglycerate (2,3-DPG) and adenosine triphosphate (ATP); both are important for normal cellular metabolism. Consequences of severe hypophosphatemia may include hemolytic anemia, seizures, altered mentation, cardiomyopathy, and skeletal muscle weakness. Parenteral phosphate therapy is necessary in most cases of severe hypophosphatemia.
严重低磷血症（即血清磷浓度低于1mg/dl）在兽医临床病例中并不常见。它最常与小动物的糖尿病酮症酸中毒有关。磷酸盐是生成2,3-二磷酸甘油酸（2,3-DPG）和三磷酸腺苷（ATP）所必需的；二者对正常细胞代谢都很重要。严重低磷血症的后果可能包括溶血性贫血、癫痫发作、精神状态改变、心肌病和骨骼肌无力。在大多数严重低磷血症病例中，需要进行肠外磷酸盐治疗。
