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预测生态基因组学:高科技动物仪器与高通量测序相遇

Forecasting Ecological Genomics: High-Tech Animal Instrumentation Meets High-Throughput Sequencing.

作者信息

Shafer Aaron B A, Northrup Joseph M, Wikelski Martin, Wittemyer George, Wolf Jochen B W

机构信息

Uppsala University, Department of Ecology and Genetics, Uppsala, Sweden.

Colorado State University, Department of Fish, Wildlife, and Conservation Biology, Fort Collins, Colorado, United States of America.

出版信息

PLoS Biol. 2016 Jan 8;14(1):e1002350. doi: 10.1371/journal.pbio.1002350. eCollection 2016 Jan.

Abstract

Recent advancements in animal tracking technology and high-throughput sequencing are rapidly changing the questions and scope of research in the biological sciences. The integration of genomic data with high-tech animal instrumentation comes as a natural progression of traditional work in ecological genetics, and we provide a framework for linking the separate data streams from these technologies. Such a merger will elucidate the genetic basis of adaptive behaviors like migration and hibernation and advance our understanding of fundamental ecological and evolutionary processes such as pathogen transmission, population responses to environmental change, and communication in natural populations.

摘要

动物追踪技术和高通量测序的最新进展正在迅速改变生物科学研究的问题和范围。基因组数据与高科技动物仪器的整合是生态遗传学传统工作的自然发展,我们提供了一个框架,用于连接来自这些技术的不同数据流。这种融合将阐明迁徙和冬眠等适应性行为的遗传基础,并推进我们对病原体传播、种群对环境变化的反应以及自然种群中的通讯等基本生态和进化过程的理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ebf5/4712824/5bb42f385954/pbio.1002350.g001.jpg

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