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血小板减少症中血小板相关IgG的检测与定量:免疫荧光法与免疫酶法的比较

Detection and quantitation of platelet-associated IgG in thrombocytopenia: a comparison of immunofluorescence and immunoenzyme techniques.

作者信息

Smith G A, Herron R

出版信息

Med Lab Sci. 1989 Jan;46(1):45-9.

PMID:2674579
Abstract

A platelet suspension immunofluorescence test (PIFT) was compared with an enzyme-linked immunosorbent assay (ELISA) for measurement of platelet-associated IgG (PAIgG) in 108 patients with thrombocytopenia. The ELISA appeared to have greater sensitivity than the PIFT in detecting PAIgG in patients with idiopathic thrombocytopenic purpura, and in other groups of patients studied, and in many cases results were discrepant between the two assays. Possible explanations are given for the low sensitivity of the PIFT, and for the discrepant results.

摘要

对108例血小板减少症患者进行了血小板悬液免疫荧光试验(PIFT)与酶联免疫吸附测定(ELISA),以检测血小板相关IgG(PAIgG)。在检测特发性血小板减少性紫癜患者、其他所研究的患者群体中的PAIgG时,ELISA似乎比PIFT具有更高的灵敏度,并且在许多情况下,两种检测方法的结果存在差异。文中给出了PIFT灵敏度低以及结果存在差异的可能原因。

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Detection and quantitation of platelet-associated IgG in thrombocytopenia: a comparison of immunofluorescence and immunoenzyme techniques.血小板减少症中血小板相关IgG的检测与定量:免疫荧光法与免疫酶法的比较
Med Lab Sci. 1989 Jan;46(1):45-9.
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