Department of General Practice, Faculty of Poitiers, 86000 Poitiers, France
UMR 5558, Laboratoire de Biométrie et Biologie Evolutive, Claude Bernard University. CNRS, Lyon, France Louis Pradel Hospital, Lyon University, Lyon, France.
BMJ. 2016 Jan 8;352:h6748. doi: 10.1136/bmj.h6748.
Rémy Boussageon and colleagues ask whether metformin is bringing practical benefit to patients and question the focus on surrogate measures.
雷米·布沙东及其同事探讨二甲双胍是否能给患者带来实际获益,并对关注替代指标提出质疑。