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巴西一项基于全国人口的抑郁症研究。

A nationwide population-based study of depression in Brazil.

作者信息

Munhoz Tiago N, Nunes Bruno P, Wehrmeister Fernando C, Santos Iná S, Matijasevich Alicia

机构信息

Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.

Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil; Department of Preventive Medicine, Faculty of Medicine, University of São Paulo, São Paulo, Brazil.

出版信息

J Affect Disord. 2016 Mar 1;192:226-33. doi: 10.1016/j.jad.2015.12.038. Epub 2015 Dec 29.

Abstract

INTRODUCTION

The state of mental health of the population is considered to be an important and essential component of public health. Depression is the mental disorder with greatest prevalence in several countries around the world.

METHODS

This was a nationwide Brazilian survey with household-based interviews. The sampling process was at random and cluster-based, and performed in three stages: census tracts, households and individuals. One inhabitant aged ≥18 years was selected per household. Individuals at greater risk of depression were identified through the Patient Health Questionnaire-9 (PHQ-9) algorithm, which uses internationally accepted diagnostic criteria. All analyses took into account sample weights.

RESULTS

A total of 60,202 individuals were evaluated and the prevalence of positive screening for depression was 4.1% (95% CI: 3.8-4.4%). After adjustments for potential confounding factors, depression was found to be greater among women, individuals aged either 40-59 years or 80 years or over, individuals living in urban areas, those with lower educational level, smokers, and among individuals with arterial hypertension, diabetes and heart disorders. Skin colour, marital status and alcohol abuse were not associated with depression.

LIMITATIONS

Characteristics of respondents and non-respondents in the sample could not be compared because data about non-respondents was not available.

CONCLUSIONS

The prevalence of positive screening for depression in Brazil was similar to other studies conducted worldwide. In Brazil, this proportion reflects a considerable absolute number of people with greater risk of depression (≈5.5 million) that may require adequate management through the health system and services.

摘要

引言

人群心理健康状况被视为公共卫生的重要且关键组成部分。抑郁症是全球多个国家中患病率最高的精神障碍。

方法

这是一项在巴西全国范围内基于家庭访谈的调查。抽样过程是随机且基于整群抽样的,分三个阶段进行:普查区、家庭和个人。每户选取一名年龄≥18岁的居民。通过患者健康问卷9项(PHQ - 9)算法识别抑郁症风险较高的个体,该算法采用国际公认的诊断标准。所有分析均考虑了样本权重。

结果

共评估了60202名个体,抑郁症筛查阳性患病率为4.1%(95%置信区间:3.8 - 4.4%)。在对潜在混杂因素进行调整后,发现女性、年龄在40 - 59岁或80岁及以上的个体、居住在城市地区的个体、教育水平较低的个体、吸烟者以及患有动脉高血压、糖尿病和心脏病的个体患抑郁症的比例更高。肤色、婚姻状况和酗酒与抑郁症无关。

局限性

由于没有无应答者的数据,无法比较样本中有应答者和无应答者的特征。

结论

巴西抑郁症筛查阳性患病率与全球其他研究相似。在巴西,这一比例反映出相当数量的抑郁症高风险人群(约550万),可能需要通过卫生系统和服务进行适当管理。

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