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新冠大流行对巴西南部基于人群的出生队列中母亲抑郁症状的影响。

Impact of covid-19 pandemic over depressive symptoms among mothers from a population-based birth cohort in southern brazil.

机构信息

Programa de Pós-Graduação Em Epidemiologia, Faculdade de Medicina, Universidade Federal de Pelotas, Rua Marechal Deodoro, 1160, 3º Piso, Pelotas, RS, CEP 96020-220, Brazil.

Departamento de Medicina Preventiva, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.

出版信息

Arch Womens Ment Health. 2023 Aug;26(4):513-521. doi: 10.1007/s00737-023-01331-2. Epub 2023 May 25.

Abstract

PURPOSE

Our aim was to assess the impact of COVID-19 on depressive symptoms among mothers from a population-based birth cohort in Pelotas, Southern Brazil.

METHODS

A subgroup of mothers from the Pelotas 2004 Birth Cohort was assessed pre-pandemic (November,2019 to March,2020) and mid-pandemic (August-December,2021). In both follow-ups, depressive symptoms were assessed using the Edinburgh Postnatal Depression Scale (EPDS). Pre-pandemic (T) and pandemic-related predictors (T) were analyzed. Prevalence of depression (EPDS score ≥ 13) at T and T were compared with chi-square test. Changes in EPDS from T to T were estimated by multivariate latent change score modelling.

RESULTS

1,550 women were assessed. Prevalence of depression increased 38.1% (from 18.9% at T to 26.1% at T) (p < 0.001). At T, higher schooling, higher family income and being employed or working were related to lower EPDS, whereas being beneficiary of a cash transfer program and a larger number of people living in the household predicted higher EPDS. The deterioration of ones' own perception of quality of overall health (β = 0.191; SE = 0.028; p < 0.001) and worst family financial situation due to the pandemic (β = 0.083; SE = 0.024; p = 0.001) predicted the increase in EPDS from T to T.

CONCLUSION

Almost two years after the beginning of the pandemic, the prevalence of depressive symptoms among the women was higher than before the pandemic. The deterioration of ones' own perception of quality of overall health and worst family financial situation due to the pandemic are proxies for the effect of COVID-19 pandemic (the true exposure of interest) in the women mental health.

摘要

目的

本研究旨在评估 COVID-19 对巴西南部皮拉塔斯(Pelotas)人群为基础的出生队列中母亲抑郁症状的影响。

方法

皮拉塔斯 2004 年出生队列的一组母亲在疫情前(2019 年 11 月至 2020 年 3 月)和疫情期间(2021 年 8 月至 12 月)进行了评估。在两次随访中,均使用爱丁堡产后抑郁量表(Edinburgh Postnatal Depression Scale,EPDS)评估抑郁症状。分析了疫情前(T)和与疫情相关的预测因素(T)。采用卡方检验比较 T 时和 T 时的抑郁发生率(EPDS 评分≥13)。采用多变量潜在变化得分模型估计 T 至 T 时 EPDS 的变化。

结果

共评估了 1550 名女性。抑郁发生率增加了 38.1%(从 T 时的 18.9%增加到 T 时的 26.1%)(p<0.001)。在 T 时,较高的教育程度、较高的家庭收入和就业或工作与较低的 EPDS 相关,而获得现金转移计划和家庭人口较多则预示着 EPDS 较高。自身对整体健康状况的感知恶化(β=0.191;SE=0.028;p<0.001)和因疫情导致家庭经济状况恶化(β=0.083;SE=0.024;p=0.001)预测了 T 至 T 时 EPDS 的增加。

结论

在疫情开始近两年后,女性的抑郁症状发生率高于疫情前。自身对整体健康状况的感知恶化和因疫情导致家庭经济状况恶化是 COVID-19 大流行对女性心理健康影响的代表(真正的感兴趣暴露)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e526/10208911/7d96f874d6e9/737_2023_1331_Fig1_HTML.jpg

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