Shin Cheolmin, Kim Yoonjung, Park Suyeon, Yoon Seoyoung, Ko Young Hoon, Kim Yong Ku, Kim Seung Hyun, Jeon Sang Won, Han Changsu
Department of Psychiatry, Korea University College of Medicine, Korea University Ansan Hospital, Ansan, Korea.
Division of Health and Nutrition Survey, Centers for Disease Control and Prevention, Cheongju, Korea.
J Korean Med Sci. 2017 Nov;32(11):1861-1869. doi: 10.3346/jkms.2017.32.11.1861.
Depressive disorder is a common mental illness and remains a major cause of morbidity worldwide. The present study, a cross-sectional, nationwide, population-based survey assessed the prevalence of depression in the general population of Korea through a random sampling of the non-institutionalized population for the Korea National Health and Nutrition Examination Survey (KNHANES) VI. The Patient Health Questionnaire (PHQ)-9 was first introduced into the KNHANES to detect depression. The point prevalence of depression (PHQ score of 10 or higher) was 6.7% (95% confidence interval [CI], 5.7-7.6) in 4,949 subjects. Based on the analysis using the diagnostic algorithm of the PHQ-9, the prevalence of major depressive disorder was 2.7% (95% CI, 2.2-3.3). Multiple logistic regression analysis, after adjusting the sociodemographic variables, also showed that the factors associated with depression were perceived stress and health status. This study reported for the first time that the point prevalence of depression screened using the PHQ-9 in this nationwide survey of the Korean population was similar to that of the western countries. As the KNHANES to detect depression is conducted biennially, further studies on the accumulated data are expected in the future.
抑郁症是一种常见的精神疾病,仍是全球发病的主要原因。本研究是一项基于全国人口的横断面调查,通过对韩国国民健康与营养检查调查(KNHANES)VI的非机构化人口进行随机抽样,评估了韩国普通人群中抑郁症的患病率。患者健康问卷(PHQ)-9首次被引入KNHANES以检测抑郁症。在4949名受试者中,抑郁症的时点患病率(PHQ评分10分及以上)为6.7%(95%置信区间[CI],5.7-7.6)。根据使用PHQ-9诊断算法的分析,重度抑郁症的患病率为2.7%(95%CI,2.2-3.3)。在调整社会人口统计学变量后的多因素logistic回归分析还显示,与抑郁症相关的因素是感知压力和健康状况。本研究首次报告,在这项对韩国人群的全国性调查中,使用PHQ-9筛查出的抑郁症时点患病率与西方国家相似。由于检测抑郁症的KNHANES每两年进行一次,预计未来将对积累的数据进行进一步研究。