Goodale Elizabeth C, Outerbridge Catherine A, White Stephen D
William R. Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California - Davis, 1 Garrod Drive, Davis, CA, 95616, USA.
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California - Davis, 1 Garrod Drive, Davis, CA, 95616, USA.
Vet Dermatol. 2016 Feb;27(1):3-e2. doi: 10.1111/vde.12283. Epub 2015 Dec 21.
Aspergillus spp. are saprophytic opportunistic fungal organisms and are a common cause of otomycosis in humans. Although there have been case reports of Aspergillus otitis externa in dogs, to the best of the authors' knowledge, this is the first retrospective case series describing Aspergillus otitis in dogs and cats.
To characterize signalment, putative risk factors, treatments and outcomes of a case series of dogs and cats with Aspergillus otitis.
Eight dogs and nine cats diagnosed with Aspergillus otitis.
A retrospective review of medical records from 1989 to 2014 identified animals diagnosed with Aspergillus otitis based on culture.
All dogs weighed greater than 23 kg. The most common putative risk factors identified in this study were concurrent diseases, therapy causing immunosuppression or a history of an otic foreign body. Aspergillus otitis was unilateral in all study dogs and most cats. Concurrent otitis media was confirmed in three dogs and one cat, and suspected in two additional cats. Aspergillus fumigatus was the most common isolate overall and was the dominant isolate in cats. Aspergillus niger and A. terreus were more commonly isolated from dogs. Animals received various topical and systemic antifungal medications; however, otic lavage under anaesthesia and/or surgical intervention increased the likelihood of resolution of the fungal infection.
Aspergillus otitis is uncommon, typically seen as unilateral otitis externa in cats and larger breed dogs with possible risk factors that include immunosuppression and otic foreign bodies; previous antibiotic usage was common.
曲霉属真菌是腐生性机会性真菌生物体，是人类耳真菌病的常见病因。虽然已有犬外耳道曲霉病的病例报告，但据作者所知，这是首个描述犬猫曲霉性中耳炎的回顾性病例系列。
描述一组患有曲霉性中耳炎的犬猫的特征、可能的危险因素、治疗方法及预后。
8只犬和9只猫被诊断患有曲霉性中耳炎。
对1989年至2014年的病历进行回顾性研究，根据培养结果确定诊断为曲霉性中耳炎的动物。
所有犬的体重均超过23千克。本研究中确定的最常见的可能危险因素是并发疾病、导致免疫抑制的治疗或耳部异物史。在所有研究的犬和大多数猫中，曲霉性中耳炎为单侧性。3只犬和1只猫确诊并发中耳炎，另外2只猫疑似并发中耳炎。烟曲霉是总体上最常见的分离菌株，也是猫中的主要分离菌株。黑曲霉和土曲霉更常见于犬。动物接受了各种局部和全身抗真菌药物治疗；然而，麻醉下耳部灌洗和/或手术干预增加了真菌感染消退的可能性。
曲霉性中耳炎并不常见，通常表现为猫和大型犬的单侧外耳道炎，可能的危险因素包括免疫抑制和耳部异物；既往抗生素使用很常见。
