Centre of Oral Health Research, School of Dental Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4BW, UK.
Centre for Oral Growth and Development (Dental Physical Sciences), Institute of Dentistry, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UK.
Dent Mater. 2016 Feb;32(2):200-10. doi: 10.1016/j.dental.2015.11.025. Epub 2015 Dec 31.
To develop two experimental temporary crown and bridge materials with improved physicomechanical properties.
Commercial materials: Trim (TR, monomethacrylate, Bosworth) and Quicktemp2 (QT, dimethacrylate, Schottlander).
isobutyl methacrylate/poly(ethyl methacrylate) (IBMA/PEM) and n-butyl methacrylate/PEM (nBMA/PEM), both monomethacrylates. For water absorption/desorption studies rectangular samples (40 mm × 10 mm × 1 mm) of each material were prepared, immersed in deionized water (DW, control) and artificial saliva (AS), and weighed at regular time intervals. %solubility and diffusion coefficients (D) for uptake/loss processes were calculated and compared with theoretical predictions. Polymerization exotherm (cylindrical samples 10 mm × 18 mm) and flexural moduli were measured (three point bending; rectangular samples 80 mm × 10 mm × 4 mm, dry and after 9 days storage in DW). The data were compared statistically.
QT and nBMA/PEM had lower %equilibrium uptakes/loss in DW (0.68%/0.884% and 0.64%/0.895% respectively). QT had the lowest water absorption/desorption D (P<0.05) compared to the three monomethacrylates, in DW and AS. %solubility for all systems showed no differences in DW (P>0.05), but a difference for QT in AS (P<0.05). QT reached its maximum temperature rapidly (∼2 min; 3 monomethacrylates ∼7-13 min). The commercial materials exhibited high peak temperatures (∼51°C, P<0.05; experimental materials ∼43°C). QT had a higher flexural modulus (∼4 GPa; 3 monomethacrylates ∼0.7-1 GPa) for dry and wet samples. The moduli for commercial materials reduced significantly after immersion in DW; there was no difference between the dry and wet experimental materials samples (P>0.05).
The experimental materials merit further studies since they presented with lower setting exotherms, and contained no phthalate plasticizer, thus being less of a risk to patients.
开发两种具有改良物理机械性能的实验性临时冠桥材料。
商业材料：Trim（TR，单甲基丙烯酸酯，Bosworth）和 Quicktemp2（QT，双甲基丙烯酸酯，Schottlander）。
异丁基甲基丙烯酸酯/聚甲基丙烯酸乙酯（IBMA/PEM）和正丁基甲基丙烯酸酯/PEM（nBMA/PEM），均为单甲基丙烯酸酯。为了进行水吸收/解吸研究，制备了每种材料的 40mm×10mm×1mm 矩形样品，将其浸入去离子水（DW，对照）和人工唾液（AS）中，并在规定的时间间隔进行称重。计算了吸收率/损失过程的溶解度和扩散系数（D），并与理论预测值进行了比较。测量了聚合放热（圆柱形样品 10mm×18mm）和弯曲弹性模量（三点弯曲；矩形样品 80mm×10mm×4mm，干燥和在 DW 中储存 9 天后）。对数据进行了统计学比较。
QT 和 nBMA/PEM 在 DW 中的平衡吸收率/损失较低（分别为 0.68%/0.884%和 0.64%/0.895%）。与三种单甲基丙烯酸酯相比，QT 在 DW 和 AS 中的水吸收/解吸 D 最低（P<0.05）。所有系统的溶解度在 DW 中没有差异（P>0.05），但在 AS 中 QT 有差异（P<0.05）。QT 迅速达到最高温度（约 2 分钟；三种单甲基丙烯酸酯约 7-13 分钟）。商用材料显示出较高的峰值温度（约 51°C，P<0.05；实验材料约 43°C）。QT 具有较高的弯曲弹性模量（约 4GPa；三种单甲基丙烯酸酯约 0.7-1GPa），无论是干燥样品还是湿样品。商用材料在浸入 DW 后弹性模量显著降低；干燥和湿实验材料样品之间没有差异（P>0.05）。
实验材料值得进一步研究，因为它们的设定放热较低，且不含邻苯二甲酸酯增塑剂，因此对患者的风险较小。
