Metcalf Olivia, Varker Tracey, Forbes David, Phelps Andrea, Dell Lisa, DiBattista Ashley, Ralph Naomi, O'Donnell Meaghan
Phoenix Centre for Posttraumatic Mental Health, Department of Psychiatry, University of Melbourne, Melbourne, Australia.
The Community Head Injury Resource Service of Toronto (CHIRS), Neurobehavioural Interventions Program, Toronto, Canada.
J Trauma Stress. 2016 Feb;29(1):88-92. doi: 10.1002/jts.22070. Epub 2016 Jan 7.
Although there is an abundance of novel interventions for the treatment of posttraumatic stress disorder (PTSD), often their efficacy remains unknown. This systematic review assessed the evidence for 15 new or novel interventions for the treatment of PTSD. Studies that investigated changes to PTSD symptoms following the delivery of any 1 of the 15 interventions of interest were identified through systematic literature searches. There were 19 studies that met the inclusion criteria for this study. Eligible studies were assessed against methodological quality criteria and data were extracted. The majority of the 19 studies were of poor quality, hampered by methodological limitations, such as small sample sizes and lack of control group. There were 4 interventions, however, stemming from a mind-body philosophy (acupuncture, emotional freedom technique, mantra-based meditation, and yoga) that had moderate quality evidence from mostly small- to moderate-sized randomized controlled trials. The active components, however, of these promising emerging interventions and how they related to or were distinct from established treatments remain unclear. The majority of emerging interventions for the treatment of PTSD currently have an insufficient level of evidence supporting their efficacy, despite their increasing popularity. Further well-designed controlled trials of emerging interventions for PTSD are required.
尽管有大量用于治疗创伤后应激障碍（PTSD）的新型干预措施，但它们的疗效往往仍不明确。本系统评价评估了15种治疗PTSD的新的或新颖的干预措施的证据。通过系统的文献检索，确定了那些研究了15种感兴趣的干预措施中任何一种实施后PTSD症状变化的研究。有19项研究符合本研究的纳入标准。对符合条件的研究依据方法学质量标准进行评估并提取数据。这19项研究中的大多数质量较差，受到方法学限制的阻碍，如样本量小和缺乏对照组。然而，有4种源于身心理念的干预措施（针灸、情绪释放技术、基于咒语的冥想和瑜伽），大多来自小到中等规模的随机对照试验，有中等质量的证据。然而，这些有前景的新兴干预措施的活性成分以及它们与既定治疗方法的关系或区别仍不清楚。尽管越来越受欢迎，但目前大多数治疗PTSD的新兴干预措施的证据水平不足以支持其疗效。需要进一步对治疗PTSD的新兴干预措施进行精心设计的对照试验。
