Shah Neha P, Katsarelis Helen, Pazianas Michael, Dhariwal Daljit K
Dent Update. 2015 Nov;42(9):878-80, 883-4, 887-89. doi: 10.12968/denu.2015.42.9.878.
Patients taking bisphosphonates and other anti-resorptive drugs are likely to attend general dental practice. The term 'bisphosphonate'is often immediately associated with osteonecrosis of the jaws (ONJ). Risk assessment and subsequent management of these patients should be carried out taking into account all the risk factors associated with ONJ. The introduction of newer drugs, also shown to be associated with ONJ, demands increased awareness of general dental practitioners about these medications. CPD/CLINICAL RELEVANCE: This paper provides an update on medication-related ONJ and considers the effects of anti-resorptive drugs on the management of patients needing exodontia, treatment for periodontal disease and dental implant placement.
服用双膦酸盐及其他抗骨吸收药物的患者可能会前往普通牙科诊所就诊。“双膦酸盐”一词常常立刻让人联想到颌骨坏死（ONJ）。对这些患者进行风险评估及后续管理时，应考虑到与ONJ相关的所有风险因素。新型药物的出现也被证明与ONJ有关，这就要求普通牙科医生提高对这些药物的认识。继续职业发展/临床相关性：本文提供了与药物相关的ONJ的最新情况，并探讨了抗骨吸收药物对需要拔牙、治疗牙周疾病及植入牙种植体的患者管理的影响。
