da Silva Rodolfo R, Moraes Marcilio M, Camara Claudio A G, Ramos Clécio S
Nat Prod Commun. 2015 Nov;10(11):1809-10.
This present work addresses research on the discovery of new compounds from natural sources. It is based on a study of Mangifera indica leaf metabolism by the Tropidacris collaris grasshopper. We found that the grasshopper hydrolyzed the flavonoid isoquercitrin to quercetin when the O-glycosidic bond was broken and sugar released as a probable energy source for the insect. There was not, however, hydrolysis of the major compound in the leaves, mangiferin, which contains the C-glycosidic bond. All compounds were isolated and their chemical structure determined by UV, IR, MS, 1H and 13C NMR.
本研究致力于从天然来源中发现新化合物。它基于对芒果叶被热带大蚱蜢代谢的研究。我们发现,当O-糖苷键断裂且糖作为昆虫可能的能量来源释放时,蚱蜢会将类黄酮异槲皮苷水解为槲皮素。然而,叶子中的主要化合物芒果苷含有C-糖苷键,并未发生水解。所有化合物均被分离出来,并通过紫外光谱、红外光谱、质谱、氢核磁共振和碳核磁共振确定其化学结构。