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瑞士年轻男性使用电子烟情况:吸电子烟是减少吸烟或戒烟的有效方式吗?

E-cigarette use in young Swiss men: is vaping an effective way of reducing or quitting smoking?

作者信息

Gmel Gerhard, Baggio Stéphanie, Mohler-Kuo Meichun, Daeppen Jean-Bernard, Studer Joseph

机构信息

Alcohol Treatment Centre, Lausanne University Hospital CHUV, Lausanne, Switzerland; Addiction Switzerland, Lausanne, Switzerland Centre for Addiction and Mental Health, Toronto, Ontario, Canada; University of the West of England, Bristol, United Kingdom.

Life course and social inequality research centre, University of Lausanne, Lausanne, Switzerland.

出版信息

Swiss Med Wkly. 2016 Jan 11;146:w14271. doi: 10.4414/smw.2016.14271. eCollection 2016.

Abstract

QUESTION UNDER STUDY

To test longitudinally differences in conventional cigarette use (cigarettes smoked, cessation, quit attempts) between vapers and nonvapers.

METHODS

Fifteen months follow-up of a sample of 5 128 20-year-old Swiss men. The onset of conventional cigarette (CC) use among nonsmokers, and smoking cessation, quit attempts, changes in the number of CCs smoked among smokers at baseline were compared between vapers and nonvapers at follow-up, adjusted for nicotine dependence.

RESULTS

Among baseline nonsmokers, vapers were more likely to start smoking at follow-up than nonvapers (odds ratio [OR] 6.02, 95% confidence interval [CI] 2.81, 12.88 for becoming occasional smokers, and OR = 12.69, 95% CI 4.00, 40.28 for becoming daily smokers). Vapers reported lower smoking cessation rates among occasional smokers at baseline (OR = 0.43 (0.19, 0.96); daily smokers: OR = 0.42 [0.15, 1.18]). Vapers compared with nonvapers were heavier CC users (62.53 vs 18.10 cigarettes per week, p <0.001) and had higher nicotine dependence levels (2.16 vs 0.75, p <0.001) at baseline. The number of CCs smoked increased between baseline and follow-up among occasional smokers (b = 6.06, 95% CI 4.44, 7.68) and decreased among daily smokers (b = -5.03, 95% CI -8.69, -1.38), but there were no differential changes between vapers and nonvapers. Vapers showed more quit attempts at follow-up compared with nonvapers for baseline occasional smokers (incidence rate ratio [IRR] 1.81, 95% CI 1.24, 2.64; daily smokers IRR 1.28, 95% CI 0.95, 1.73).

CONCLUSIONS

We found no beneficial effects of vaping at follow-up for either smoking cessation or smoking reduction.

摘要

研究问题

纵向测试电子烟使用者和非电子烟使用者在传统香烟使用(吸烟量、戒烟、戒烟尝试)方面的差异。

方法

对5128名20岁瑞士男性样本进行15个月的随访。在随访时,比较电子烟使用者和非电子烟使用者中,非吸烟者开始使用传统香烟(CC)的情况,以及吸烟者的戒烟、戒烟尝试情况,和基线时CC吸烟量的变化,并对尼古丁依赖进行了校正。

结果

在基线非吸烟者中,随访时电子烟使用者比非电子烟使用者更有可能开始吸烟(成为偶尔吸烟者的优势比[OR]为6.02,95%置信区间[CI]为2.81, 12.88;成为每日吸烟者的OR = 12.69,95% CI为4.00, 40.28)。电子烟使用者报告基线时偶尔吸烟者的戒烟率较低(OR = 0.43(0.19, 0.96);每日吸烟者:OR = 0.42 [0.15, 1.18])。与非电子烟使用者相比,电子烟使用者在基线时是更重度的CC使用者(每周62.53支对18.10支,p <0.001),且尼古丁依赖水平更高(2.16对0.75,p <0.001)。在基线和随访之间,偶尔吸烟者的CC吸烟量增加(b = 6.06,95% CI为4.44, 7.68),每日吸烟者的CC吸烟量减少(b = -5.03,95% CI为-8.69, -1.38),但电子烟使用者和非电子烟使用者之间没有差异变化。与非电子烟使用者相比,电子烟使用者在随访时基线偶尔吸烟者的戒烟尝试更多(发病率比[IRR]为1.81,95% CI为1.24, 2.64;每日吸烟者IRR为1.28,95% CI为0.95, 1.73)。

结论

我们发现在随访时,电子烟对戒烟或减少吸烟量均无有益影响。

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