[类风湿关节炎患者生物体液中β2-微球蛋白水平测定的重要性]

[Importance of determining the beta2-microglobulin level in biological fluids in patients with rheumatoid arthritis].

作者信息

Trusov V V, Bazhenov A N

出版信息

Ter Arkh. 1989;61(5):46-8.

Abstract

The level of beta 2-microglobulin (beta 2-MG) in blood and urine was measured in 97 patients with rheumatoid arthritis. In 42 of them, the measurements were made in the synovial fluid. The level of beta 2-MG was found to depend on the process activity, the magnitude of the articular count, and on the disease duration. It was shown that the drug treatment pattern influenced the content of beta 2-MG in blood, urine and synovial fluid. In 12 out of the 97 patients with rheumatoid arthritis, the measurement of beta 2-MG in blood and urine made it possible to determine the involvement of the kidneys into the pathological process.

摘要

对97例类风湿性关节炎患者的血液和尿液中的β2-微球蛋白（β2-MG）水平进行了测量。其中42例患者还对其滑液进行了测量。发现β2-MG水平取决于疾病活动程度、关节受累数量以及病程。结果表明，药物治疗方式会影响血液、尿液和滑液中β2-MG的含量。在97例类风湿性关节炎患者中，有12例通过对血液和尿液中的β2-MG进行测量，得以确定肾脏是否参与了病理过程。