Verdier J M, Cassuto J P, Viot G, Quaranta J F, Krebs B P
Nouv Presse Med. 1980 Mar 29;9(15):1073-5.
The object of this study was to determine whether levels of beta-2-microglobulin and of rheumatoid factor measured by an enzyme-immunoassay allowed good discrimination between inflammatory and degenerative arthropathies. A multiparametric study of synovial fluid was performed on 85 specimens from patients with rheumatoid arthritis, chondrocalcinosis, mechanical arthritis and traumatic arthopathies. A beta-2-microglobulin level of less than 4 mg/l is a result very mich in favor of a non-inflammatory arthropathy (48/49 cases). The quantification of intra-articular rheumatoid factor allows for reclassification in the context of sero-negative rheumatoid arthritis.
本研究的目的是确定通过酶免疫测定法测量的β-2-微球蛋白和类风湿因子水平是否能很好地区分炎症性和退行性关节病。对类风湿关节炎、软骨钙质沉着症、机械性关节炎和创伤性关节病患者的85份滑膜液标本进行了多参数研究。β-2-微球蛋白水平低于4mg/l强烈提示为非炎症性关节病（49例中有48例）。关节内类风湿因子的定量有助于在血清阴性类风湿关节炎的背景下进行重新分类。
