From the Northwestern University Medical Center, Chicago, IL.
Dermatitis. 2016 Jan-Feb;27(1):11-3. doi: 10.1097/DER.0000000000000152.
The usage prevalence of ingredients in topical products is important to dermatologists and industry.
To determine the prevalence of methylisothiazolinone (MI) in various types of consumer products
The Contact Allergy Management Program (CAMP) database was mapped and sorted in spreadsheet format to determine the prevalence of MI in various types of consumer products.
Methylisothiazolinone was found in 13.2% of 4660 total products in CAMP. High usage of MI was seen in dishwashing products (64%), shampoos (53%), bathroom/kitchen/all-purpose cleaners (47%), hair conditioners (45%), hair dyes (43%), laundry additives/fresheners/softeners (30%), soaps/cleansers (29%), and surface cleaners/disinfectants (27%). Of the products containing MI, MI alone (without methylchloroisothiazolinone) was most common in makeup products (100%), cleaning/dish/laundry products (>99%), moisturizers (82%), shaving products (78%), sunscreens (71%), and antiaging products (67%).
The American Contact Dermatitis Society's CAMP is a valuable tool to collect epidemiologic data on the incidence of specific ingredient usage in various types of topical products.
皮肤科医生和行业都非常关注外用产品成分的使用流行情况。
确定各种消费者产品中甲基异噻唑啉酮(MI)的使用流行情况。
对接触性皮炎管理计划(CAMP)数据库进行映射和电子表格格式排序,以确定各种消费者产品中 MI 的使用流行情况。
在 CAMP 的 4660 种总产品中,发现 MI 占 13.2%。在餐具清洗产品(64%)、洗发水(53%)、浴室/厨房/多用清洁剂(47%)、护发素(45%)、染发剂(43%)、衣物添加剂/清新剂/柔软剂(30%)、肥皂/清洁剂(29%)和表面清洁剂/消毒剂(27%)中,MI 的使用频率较高。在含有 MI 的产品中,单独的 MI(不含甲基氯异噻唑啉酮)在化妆品产品(100%)、清洁/餐具/衣物产品(>99%)、保湿霜(82%)、剃须产品(78%)、防晒霜(71%)和抗衰老产品(67%)中最为常见。
美国接触性皮炎学会的 CAMP 是收集各种类型外用产品中特定成分使用的发病率的流行病学数据的有价值工具。